Update: biological and chemical aspects of Nectandra genus (Lauraceae)

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dc.contributor.author Grecco, Simone dos Santos [UNIFESP]
dc.contributor.author Lorenzi, Harry
dc.contributor.author Tempone, Andre G.
dc.contributor.author Lago, Joao Henrique Ghilardi [UNIFESP]
dc.date.accessioned 2020-07-31T12:47:44Z
dc.date.available 2020-07-31T12:47:44Z
dc.date.issued 2016
dc.identifier http://dx.doi.org/10.1016/j.tetasy.2016.07.009
dc.identifier.citation Tetrahedron-Asymmetry. Oxford, v. 27, n. 17-18, p. 793-810, 2016.
dc.identifier.issn 0957-4166
dc.identifier.uri https://repositorio.unifesp.br/handle/11600/57051
dc.description.abstract The genus Nectandra, composed by approximately 120 species that are distributed in the tropical and subtropical regions of America, Africa, Asia, and Oceania, belongs to the Lauraceae family. Plants from this genus, usually trees, have been used in folk medicine as anti-inflammatory, analgesic, antifungal and antiprotozoal reagents en
dc.description.abstract its biological potential has been reported in several studies conducted in vitro and in vivo. Chemically, the genus Nectandra contains different types of secondary metabolites, such as alkaloids (aporphine, proaporphine, benzylisoquinoline, bisbenzylisoquinoline, and morphinandienone) and lignoids (furofuran, benzofuran, tetrahydrofuran, dihydrofuran, and 3,3-neolignan). Other compounds, such as terpenoids (mainly mono and sesquiterpenes), steroids, phenylpropanoids and flavonoids have been described in Nectandra genus. Other minor derivatives such as coumarins, benzoic acid derivatives, xanthone, benzophenones, lactones, sugars and fatty acids have also been isolated. Most of these studies associate biological aspects to isolated compounds. In this review, we provide a comprehensive overview of the chemistry of the genus Nectandra and compile approximately 200 compounds isolated from different species, together with their therapeutic potential. (C) 2016 Elsevier Ltd. All rights reserved. en
dc.format.extent 793-810
dc.language.iso eng
dc.publisher Pergamon-Elsevier Science Ltd
dc.relation.ispartof Tetrahedron-Asymmetry
dc.rights Acesso restrito
dc.title Update: biological and chemical aspects of Nectandra genus (Lauraceae) en
dc.type Artigo
dc.description.affiliation Fed Univ ABC, Ctr Nat Sci & Humanities, BR-09210180 Sao Paulo, Brazil
dc.description.affiliation Univ Fed Sao Paulo, Inst Environm Chem & Pharmaceut Sci, BR-09972270 Sao Paulo, Brazil
dc.description.affiliation Plantarum Inst Flora Studies, BR-13460000 Sao Paulo, Brazil
dc.description.affiliation Adolfo Lutz Inst, Ctr Parasitol & Mycol, BR-01246902 Sao Paulo, Brazil
dc.description.affiliationUnifesp Institute of Environmental, Chemical and Pharmaceutical Sciences, Universidade Federal de São Paulo (UNIFESP), São Paulo 09972-270, Brazil
dc.identifier.doi 10.1016/j.tetasy.2016.07.009
dc.description.source Web of Science
dc.identifier.wos WOS:000383295500001
dc.coverage Oxford
dc.citation.volume 27
dc.citation.issue 17-18


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