The adipose tissue and the involvement of the renin-angiotensin-aldosterone system in cardiometabolic syndrome

The adipose tissue and the involvement of the renin-angiotensin-aldosterone system in cardiometabolic syndrome

Author Borghi, F. Google Scholar
Sevá-Pessôa, Bruno Autor UNIFESP Google Scholar
Grassi-Kassisse, D. M. Google Scholar
Abstract Cardiometabolic diseases are linked to a cluster of modifiable factors, including risk factors closely related to central adiposity. Chronic renin-angiotensin-aldosterone system (RAAS) activation has far-reaching effects on cardiometabolic risk and is a substantial contributor to this clinical condition. RAAS components are locally expressed in the vessels and adipose tissue. This review appoints RAAS, through the classical and the alternative view, as the main mediator of the cross-talk in cardiometabolic syndrome.
Keywords Adipose tissue
Angiotensin
Cardiometabolic syndrome
Renin-angiotensin-aldosterone system
Adiposity
xmlui.dri2xhtml.METS-1.0.item-coverage New York
Language English
Sponsor Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)
Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)
Date 2016
Published in Cell And Tissue Research. New York, v. 366, n. 3, p. 543-548, 2016.
ISSN 0302-766X (Sherpa/Romeo, impact factor)
Publisher Springer
Extent 543-548
Origin http://dx.doi.org/10.1007/s00441-016-2515-6
Access rights Closed access
Type Article
Web of Science ID WOS:000389238700004
URI https://repositorio.unifesp.br/handle/11600/56651

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