Author |
Gomes, J. S.
![]() ![]() Ducos, D. V. ![]() ![]() Gadelha, Ary ![]() ![]() Ortiz, B. B. ![]() ![]() Van Deusen, M. ![]() Akiba, H. T. ![]() ![]() Guimaraes, L. S. P. ![]() Cordeiro, Q. ![]() ![]() Trevizol, A. P. ![]() ![]() Lacerda, A. ![]() ![]() Dias, A. M. ![]() ![]() |
Abstract | Background: Cognitive impairments in schizophrenia are strongly correlated to functional outcome and recovery rates, with no pharmacological agent approved for its treatment. Neurofeedback has emerged as a non-pharmacological approach to enhance neuroplasticity, which consists in inducing voluntary control of brain responses through operant conditioning. Method: The effects of hemoencephalography neurofeedback (HEG-NFBK) in 4 brain sites (F7, Fp1, Fp2 and F8) was studied in 8 patients with schizophrenia (SCH, mean age 36.5 +/- 9.98) and 12 health controls (mean age 32.17 +/- 5.6). We analyzed groups' performance (10 sessions) and cognitive differences in 3 time points (baseline, after training and follow-up) with generalized estimated equations. For SCH we also evaluate the impact on psychopathology. Results: We found a group * time interaction for HEG-NFBK performance in the left hemisphere sites (F7 an Fp1) and a near-to-significant in the right frontotemporal region (F8), with no group differences and a significant time effect. Most of cognitive domains improved after intervention, including information processing speed, attention processing, working memory, executive functioning, verbal and visual learning. No group * time interaction was found. Results suggest that both groups benefit from HEG-NFBK training regardless of cognitive differences at baseline. No significant time effects were found for Calgary and PANSS total scale and subscales (positive, negative neither general). Conclusion: To our knowledge, this is the first controlled trial showing effects of NFBK on cognitive performance improvement in schizophrenia. Further research investigating the effects of HEG-NFBK training in schizophrenia should be performed. (C) 2017 Elsevier B.V. All rights reserved. |
Keywords |
Schizophrenia
Non-invasive brain stimulation Hemoencephalography neurofeedback Neurofeedback Psychosis |
xmlui.dri2xhtml.METS-1.0.item-coverage | Amsterdam |
Language | English |
Date | 2018 |
Published in | Schizophrenia Research. Amsterdam, v. 195, p. 591-593, 2018. |
ISSN | 0920-9964 (Sherpa/Romeo, impact factor) |
Publisher | Elsevier Science Bv |
Extent | 591-593 |
Origin |
|
Access rights | Closed access |
Type | Letter |
Web of Science ID | WOS:000432466700102 |
URI | https://repositorio.unifesp.br/handle/11600/55565 |
File | Size | Format | View |
---|---|---|---|
There are no files associated with this item. |