Low frequency of human papillomavirus detection in prostate tissue from individuals from Northern Brazil
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Data
2009-07-01
Autores
Silvestre, Rodrigo Vellasco Duarte
Leal, Mariana Ferreira [UNIFESP]
Demachki, Samia
Nahum, Márcia Cristina de Souza
Bernardes, Julio Guilherme Balieiro
Rabenhorst, Silvia Helena Barem
Smith, Marilia de Arruda Cardoso [UNIFESP]
Mello, Wyller Alencar de
Guimarães, Adriana Costa
Burbano, Rommel Rodríguez [UNIFESP]
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The presence of human papillomavirus (HPV) was evaluated in 65 samples of prostate tumours and six samples of prostates with benign prostatic hyperplasia from individuals from Northern Brazil. We used a highly sensitive test, the Linear Array HPV Genotyping Test, to detect 37 high and low-risk HPV types. In this study, only 3% of tumour samples showed HPV infection. Our findings support the conclusion that, despite the high incidence of HPV infection in the geographic regions studied, HPV was not associated with a higher risk of prostate cancer. To our knowledge, this is the first study evaluating the frequency of HPV detection in prostatic tissue of individuals from Brazil.
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Memórias do Instituto Oswaldo Cruz. Instituto Oswaldo Cruz, Ministério da Saúde, v. 104, n. 4, p. 665-667, 2009.