Fibromyalgia and Chronic Pain Syndromes A White Paper Detailing Current Challenges in the Field

Date
2016Author
Arnold, Lesley M.
Choy, Ernest
Clauw, Daniel J.
Goldenberg, Don L.
Harris, Richard E.
Helfenstein, Milton, Jr. [UNIFESP]
Jensen, Troels Staehelin
Noguchi, Koichi
Silverman, Stuart L.
Ushida, Takahiro
Wang, Guochun
Type
ArtigoISSN
0749-8047DOI
10.1097/AJP.0000000000000354Metadata
Show full item recordAbstract
This manuscript, developed by a group of chronic pain researchers and clinicians from around the world, aims to address the state of knowledge about fibromyalgia (FM) and identify ongoing challenges in the field of FM and other chronic pain syndromes that may be characterized by pain centralization/amplification/hypersensitivity. There have been many exciting developments in research studies of the pathophysiology and treatment of FM and related syndromes that have the potential to improve the recognition and management of patients with FM and other conditions with FM-like pain. However, much of the new information has not reached all clinicians, especially primary care clinicians, who have the greatest potential to use this new knowledge to positively impact their patients' lives. Furthermore, there are persistent misconceptions about FM and a lack of consensus regarding the diagnosis and treatment of FM. This paper presents a framework for future global efforts to improve the understanding and treatment of FM and other associated chronic pain syndromes, disseminate research findings, identify ways to enhance advocacy for these patients, and improve global efforts to collaborate and reach consensus about key issues related to FM and chronic pain in general.
Citation
Clinical Journal Of Pain. Philadelphia, v. 32, n. 9, p. 737-746, 2016.Keywords
fibromyalgiachronic widespread pain
central pain
sensory hypersensitivity
central amplification
central sensitivity syndromes
neuroimaging
regulatory pathway
unified diagnostic guidelines
interprofessional collaboration
Sponsorship
Pfizer Inc., New York, NYDainippon Sumitomo Pharma, Tokyo, Japan
Innovative Med Concepts LLC (IMC), Tuscaloosa, AL
Ironwood Pharmaceuticals, Cambridge, MA
Purdue Pharma, Stamford, CT
Shire, Lexington, MA
Theravance Biopharma, South San Francisco, CA
Toray, Tokyo, Japan
Eli Lilly and Company, Indianapolis, IN
Forest Laboratories, New York, NY
Tonix Pharmaceuticals, New York, NY
Cerephex Corporation, Los Altos, CA
National Institutes of Health, Bethesda, MD
National Institutes of Health
Grunenthal, Aachen Germany
Orion Pharma, Espoo, Finland
Collections
- EPM - Artigos [17701]