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dc.contributor.authorCaldeira, Luciane de Fátima [UNIFESP]
dc.contributor.authorBurattini, Marcelo Nascimento [UNIFESP]
dc.date.accessioned2015-06-14T13:39:12Z
dc.date.available2015-06-14T13:39:12Z
dc.date.issued2009-06-01
dc.identifierhttp://dx.doi.org/10.1590/S1984-82502009000200015
dc.identifier.citationBrazilian Journal of Pharmaceutical Sciences. Universidade de São Paulo, Faculdade de Ciências Farmacêuticas, v. 45, n. 2, p. 295-302, 2009.
dc.identifier.issn1984-8250
dc.identifier.urihttp://repositorio.unifesp.br/handle/11600/5040
dc.description.abstractThe objective of this study was to analyze the variation in antimicrobials' consumption and the costs related to their use at a University Hospital between 1999 and 2004. The annual consumption of nine antimicrobials, expressed in DDD/100 patients-day, and the direct costs with their acquisition were evaluated. Analysis of variance and regression techniques were used to compare data, considering a significance level of 5%. The most consumed antimicrobials were amikacin and ceftriaxone. In general, antimicrobials consumption, expressed in DDD/100 patients-day, increased from 9.21 in 1999 to 25.08 in 2004 (p<0.0001). When analyzing antimicrobial consumption as related to specific hospital units, the ICU showed the highest consumption followed by Chemotherapy and Medical Clinical units, respectively. In addition, the number of patients-day increased from 2671/month in 1999 to 3502/month in 2004, p<0.0001. As a consequence, total expenditure with antimicrobials increased from R$ 98.89 per 100 patients-day in 1999 to R$ 731.26 in 2004, p<0.0001. Between 1999 and 2004 significant increases in both consumption and financial expenditure with antimicrobials were observed.en
dc.description.abstractO trabalho teve por objetivo analisar a variação do consumo e gastos financeiros com antimicrobianos em Hospital Universitário entre 1999 e 2004. Analisou-se 9 antimicrobianos, sendo o consumo expresso em DDDs/100 pacientes-dia e o preço médio de compra obtido do relatório da farmácia hospitalar. As variações anuais no consumo, o consumo por tipo de unidades de internação e gastos com cada antimicrobiano foram estudadas por análise de variância. Adotou-se 5% como limiar de significância. Os antimicrobianos mais consumidos no período foram amicacina e ceftriaxona. Observou-se aumento no consumo dos antimicrobianos selecionados de 9,21 DDDs/100 pacientes-dia em 1999 para 25,08 em 2004 (p<0,0001). Entre as unidades de internação, a UTI apresentou o maior consumo médio, seguindo-se as unidades de Quimioterapia e Clínica Médica. A média mensal de pacientes-dia atendidos aumentou de 2671 em 1999 para 3502 em 2004 (p<0,0001). Observou-se aumento significativo nos gastos totais com antimicrobianos no período (R$ 98,89 x R$ 731,26 por 100 pacientes-dia entre 1999 e 2004, p<0,0001). Observou-se aumento significativo tanto na utilização quanto no gasto financeiro por 100 pacientes-dia diretamente relacionado à aquisição dos antimicrobianos estudados.pt
dc.format.extent295-302
dc.language.isoeng
dc.publisherUniversidade de São Paulo, Faculdade de Ciências Farmacêuticas
dc.relation.ispartofBrazilian Journal of Pharmaceutical Sciences
dc.rightsAcesso aberto
dc.subjectMedicinesen
dc.subjectAntimicrobialsen
dc.subjectPharmacoepidemiologyen
dc.subjectMedicamentospt
dc.subjectAntimicrobianospt
dc.subjectFarmacoepidemiologiapt
dc.titleAnalysis of antimicrobials' consumption profile in a University Hospital of Western Paraná, Brazilen
dc.typeArtigo
dc.contributor.institutionState University of Western Paraná Faculty of Pharmacy Department of Hospital Pharmacy
dc.contributor.institutionUniversidade Federal de São Paulo (UNIFESP)
dc.description.affiliationState University of Western Paraná Faculty of Pharmacy Department of Hospital Pharmacy
dc.description.affiliationFederal University of São Paulo Department of Medicine
dc.description.affiliationUnifespUNIFESP, Department of Medicine
dc.identifier.fileS1984-82502009000200015.pdf
dc.identifier.scieloS1984-82502009000200015
dc.identifier.doi10.1590/S1984-82502009000200015
dc.description.sourceSciELO
dc.identifier.wosWOS:000269653900015


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