Acridone alkaloids from swinglea glutinosa (rutaceae) and their effects on photosynthesis
Arato Ferreira, Pedro H. [UNIFESP]
dos Santos, Djalma A. P.
da Silva, Maria Fatima das G. F.
Vieira, Paulo C.
Veiga, Thiago A. M. [UNIFESP]
Is part ofChemistry & Biodiversity
MetadataShow full item record
Continuing our search for herbicide models based on natural products, we investigated the action mechanisms of five alkaloids isolated from Swinglea glutinosa (Rutaceae): Citrusinine-I (1), glycocitrine-IV (2), 1,3,5-trihydroxy-10-methyl-2,8-bis(3-methylbut-2-en-1-yl)-9(10H)-acridinone (3), (2R)-2-tert-butyl-3,10-dihydro-4,9-dihydroxy-11-methoxy-10-methylfuro[3,2-b]acridin-5(2H)-one (4), and (3R)-2,3,4,7-tetrahydro-3,5,8-trihydroxy-6-methoxy-2,2,7-trimethyl-12H-pyrano[2,3-a]acridin-12-one (5) on several photosynthetic activities in an attempt to find new compounds that affect photosynthesis. Through polarographic techniques, the compounds inhibited the non-cyclic electron transport in the basal, phosphorylating, and uncoupled conditions from H2O to methylviologen (=MV). Therefore, they act as Hill reaction inhibitors. This approach still suggested that the compounds 4 and 5 had their interaction site located at photosystem I. Studies on fluorescence of chlorophyll a suggested that acridones (1-3) have different modes of interaction and inhibition sites on the photosystem II electron transport chain.
CitationChemistry & Biodiversity. Weinheim, v. 13, n. 1, p. 100-106, 2016.
FAPESP, Fundacao de Amparo a Pesquisa de Estado de Sao Paulo [2010/552326-9]
DGAPA [PAPIIT IT102012-3]
- ICAQF - Artigos