Relationship between cytokines and running economy in marathon runners

Date
2016Author
Luna Junior, Luiz Antonio [UNIFESP]
Batista dos Santos, Juliana de Melo
Lacerda Bachi, Andre Luis
Foster, Roberta [UNIFESP]
Amaro, Alexandre Slowetzky
Ligeiro de Oliveira, Ana Paula
Renno Sierra, Ana Paula
Peduti Dal Molin Kiss, Maria Augusta
Vaisberg, Mauro Walter [UNIFESP]
Type
ArtigoISSN
2391-5412Is part of
Open Life SciencesDOI
10.1515/biol-2016-0041Metadata
Show full item recordAbstract
Background: Running economy (RE), expresses the relationship between the energy cost of running (Cr) and the work performed by a runner and is an predictor of performance. Given the intense effort of marathon runners during training and competition and the dearth of studies that address performance and cytokines in this population, the objective of the current study was to investigate the relationship between RE and cytokines in marathon runners. Methods: A total of 22 recreational marathon runners were examined. Using data obtained from VO2max assessments and sub-maximal tests, the following formula was applied to determine RE: Cr (mLO(2).kg(-1) . km(-1)) = VO2 (mL . kg(-1) . h(-1)) x 60 divided by speed (km . h(-1)). Results: Cr values shows no correlation with levels of the serum IL-1 beta, IL-4, IL-8, IL-10 and TNF-alpha 24h before, immediately after or 72h after the completion of an official marathon. However, the IL-6 level shows a significant correlation with Cr. Discussion and conclusion: The relationship between higher values of IL-6 and lower RE leads to the hypothesis of a physical under-recovery state by some athletes. Considering the stress caused by training, associated with the higher energetic cost in less economic athletes, it's possible that the period of resting may not totally compensate for the inflammatory state.
Citation
Open Life Sciences. Warsaw, v. 11, n. 1, p. 308-312, 2016.Keywords
Running EconomyMaximal Oxygen Consumption
Cytokine
Inflammation And Recreational AthletesPhysical-Activity
Energy-Cost
Performance
Stress
Sponsorship
Fundacao de Amparo a Pesquisa de Sao Paulo (FAPESP), Sao Paulo, Brazil [12/51698-5]Collections
- EPM - Artigos [17701]