Show simple item record

dc.contributor.authorMoreira, Karin Monteiro [UNIFESP]
dc.contributor.authorFerreira, Tatiana Lima [UNIFESP]
dc.contributor.authorHipólide, Débora Cristina [UNIFESP]
dc.contributor.authorFomari, Raquel Vecchio [UNIFESP]
dc.contributor.authorTufik, Sergio [UNIFESP]
dc.contributor.authorMenezes Oliveira, Maria Gabriela [UNIFESP]
dc.date.accessioned2018-06-18T12:11:59Z
dc.date.available2018-06-18T12:11:59Z
dc.date.issued2010-07-01
dc.identifierhttps://doi.org/10.1093/sleep/33.7.99
dc.identifier.citationSleep. Westchester: Amer Acad Sleep Medicine, v. 33, n. 7, p. 990-993, 2010.
dc.identifier.issn0161-8105
dc.identifier.urihttp://repositorio.unifesp.br/11600/45609
dc.description.abstractStudy Objectives: Evaluation of modafinil effects on the inhibitory avoidance task (IA).Design: Rats were trained on a multiple trial IA task after receiving modafinil or vehicle injections. In experiment 1 they were trained with a weak protocol under baseline condition and in experiment 2, with a stronger protocol under sleep-deprivation condition.Results: In experiment 1 modafinil improved rats' acquisition whereas the retention test remained unaffected. In Experiment 2 modafinil did not interfere with training performance, but the lower dose prevented the retention impairment in sleep-deprived animals.Conclusions: Modafinil is able to improve acquisition in normal rats and reverse the long-term memory impairment induced by sleep-deprivation.en
dc.format.extent990-993
dc.language.isoeng
dc.publisherAmer Acad Sleep Medicine
dc.relation.ispartofSleep
dc.rightsAcesso aberto
dc.subjectCognitive enhanceren
dc.subjectemotional memoryen
dc.subjectacquisitionen
dc.subjectretrievalen
dc.subjectlearningen
dc.subjectsleepen
dc.titleModafinil Prevents Inhibitory Avoidance Memory Deficit Induced by Sleep Deprivation in Ratsen
dc.typeArtigo
dc.contributor.institutionUniversidade Federal de São Paulo (UNIFESP)
dc.contributor.institutionUniversidade Federal do ABC (UFABC)
dc.contributor.institutionUniv Groningen, Univ Med Ctr Groningen
dc.description.affiliationUniv Fed Sao Paulo, Dept Psychobiol, BR-04024002 Sao Paulo, Brazil
dc.description.affiliationUniv Fed Sao Paulo, Dept Biol Sci, BR-04024002 Sao Paulo, Brazil
dc.description.affiliationUniv Fed ABC, Math Computat & Cognit Ctr, Santo Andre, SP, Brazil
dc.description.affiliationUniv Groningen, Univ Med Ctr Groningen, Dept Neurosci, NL-9713 AV Groningen, Netherlands
dc.description.affiliationUnifespUniv Fed Sao Paulo, Dept Psychobiol, BR-04024002 Sao Paulo, Brazil
dc.description.affiliationUnifespUniv Fed Sao Paulo, Dept Biol Sci, BR-04024002 Sao Paulo, Brazil
dc.description.sourceWeb of Science
dc.identifier.wosWOS:000279365600020


Files in this item

FilesSizeFormatView

There are no files associated with this item.

This item appears in the following Collection(s)

Show simple item record