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dc.contributor.authorNiccolai Costa, Anna Maria
dc.date.accessioned2018-06-18T11:54:27Z
dc.date.available2018-06-18T11:54:27Z
dc.date.issued2008-01-01
dc.identifierhttp://dx.doi.org/10.1590/S0101-60832008000300003
dc.identifier.citationRevista De Psiquiatria Clinica. Sao Paulo: Univ Sao Paulo, Inst Psiquiatria, v. 35, n. 3, p. 104-110, 2008.
dc.identifier.issn0101-6083
dc.identifier.urihttp://repositorio.unifesp.br/11600/45476
dc.description.abstractBackground: Bipolar disorder (BD) is a recurrent, chronic and severe disease. Mental and physical comorbidities, risk of suicide, health services use and impairment of social and professional domains significantly worsen the burden and increase the costs of illness. Objectives: Review clinical aspects, burden of disease, and consequent financial outcomes of BD. Methods: MEDLINE/PubMed database search using the terms bipolar disorder, epidemiology, burden of disease, comorbidity, cost of illness, outcomes e financial consequences, published in MEDLINE from 1980 to 2006. Results: BD has a high rate of comorbidities, which worsen the prognosis and increase costs with health services. Subjects with BD have more cardiovascular risk factors than the general population, and therefore a higher risk of death by cardiovascular event. Delay of diagnosis and misdiagnosis increase the costs of illness. Discussion: Comorbidities, risk of suicide, social and professional impairment and low adherence to treatment increase the cost of illness. The search of comorbidities may help clinicians to adjust treatment strategies, taking into account all associated risk factors and costs, which may be considered also by professionals involved in health care management, either private or public.en
dc.format.extent104-110
dc.language.isopor
dc.publisherUniv Sao Paulo, Inst Psiquiatria
dc.relation.ispartofRevista De Psiquiatria Clinica
dc.rightsAcesso aberto
dc.subjectpsychiatryen
dc.subjectbipolar disorderen
dc.subjectcomorbidityen
dc.subjectcost of illnessen
dc.subjectmental healthen
dc.titleTranstorno afetivo bipolar: carga da doença e custos relacionadospt
dc.title.alternativeBipolar disorder: burden of disease and related costsen
dc.typeResenha
dc.contributor.institutionBristol Myers Squibb Co
dc.contributor.institutionUniversidade Federal de São Paulo (UNIFESP)
dc.description.affiliationBristol Myers Squibb Co, New York, NY 10154 USA
dc.description.affiliationUniv Fed Sao Paulo, Dept Psiquiatria, Curso Posgrad, Sao Paulo, Brazil
dc.description.affiliationUnifespUniv Fed Sao Paulo, Dept Psiquiatria, Curso Posgrad, Sao Paulo, Brazil
dc.identifier.fileS0101-60832008000300003.pdf
dc.identifier.scieloS0101-60832008000300003
dc.identifier.doi10.1590/S0101-60832008000300003
dc.description.sourceWeb of Science
dc.identifier.wosWOS:000257955200003


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