Does Cognitive Behavioral Therapy Change the Brain? A Systematic Review of Neuroimaging in Anxiety Disorders

Does Cognitive Behavioral Therapy Change the Brain? A Systematic Review of Neuroimaging in Anxiety Disorders

Author Porto, Patricia Ribeiro Google Scholar
Oliveira, Leticia Google Scholar
Mari, Jair Autor UNIFESP Google Scholar
Volchan, Eliane Google Scholar
Figueira, Ivan Google Scholar
Ventura, Paula Google Scholar
Institution Universidade Federal do Rio de Janeiro (UFRJ)
Universidade Federal Fluminense (UFF)
Universidade Federal de São Paulo (UNIFESP)
Abstract This systematic review aims to investigate neurobiological changes related to cognitive-behavioral therapy (CBT) in anxiety disorders detected through neuroimaging techniques and to identify predictors of response to treatment. Cognitive-behavioral therapy modified the neural circuits involved in the regulation of negative emotions and fear extinction in judged treatment responders. The only study on predictors of response to treatment was regarding obsessive-compulsive disorder and showed higher pretreatment regional metabolic activity in the left orbitofrontal cortex associated with a better response to behavioral therapy. Despite methodological limitations, neuroimaging studies revealed that CBT was able to change dysfunctions of the nervous system.
Language English
Date 2009-05-01
Published in Journal Of Neuropsychiatry And Clinical Neurosciences. Arlington: Amer Psychiatric Publishing, Inc, v. 21, n. 2, p. 114-125, 2009.
ISSN 0895-0172 (Sherpa/Romeo, impact factor)
Publisher Amer Psychiatric Publishing, Inc
Extent 114-125
Origin http://dx.doi.org/10.1176/jnp.2009.21.2.114
Access rights Closed access
Type Review
Web of Science ID WOS:000268152300002
URI http://repositorio.unifesp.br/11600/44516

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