Gastroduodenal lesions in children with juvenile rheumatoid arthritis
Nenhuma Miniatura disponível
Data
1999-03-01
Autores
Len, Claudio Arnaldo [UNIFESP]
Hilário, Maria Odete Esteves [UNIFESP]
Kawakami, Elisabete [UNIFESP]
Terreri, Maria Teresa Ramos Ascensão [UNIFESP]
Becker, D. J.
Goldenberg, José [UNIFESP]
Fagundes Neto, Ulysses [UNIFESP]
Orientadores
Tipo
Artigo
Título da Revista
ISSN da Revista
Título de Volume
Resumo
BACKGROUND/AIMS: There are few studies about gastrointestinal abnormalities in patients with juvenile rheumatoid arthritis - probably due to the fact that this association is not frequently recognized. The aim of our study was to observe the prevalence of endoscopic gastroduodenal lesions in these patients.METHODOLOGY: Fourteen patients with juvenile rheumatoid arthritis, all of them using non-steroidal anti-inflammatory drugs associated or not with methotrexate, were assessed clinically and by endoscopy. Gastric antrum biopsy and Helicobacter pylori search were also performed.RESULTS: The mean age of the patients was 10.6 years (7 boys). Abdominal pain was observed in 27% of them. Macroscopic endoscopic lesions were found in 43% and infection by Helicobacter pylori in 57%. The correlation between anemia and endoscopic abnormalities was statistically significant (p<0.05).CONCLUSIONS: Our data show that patients with juvenile rheumatoid arthritis have considerable susceptibility to gastroduodenal lesions, especially if they are using any drug association and present anemia.
Descrição
Citação
Hepato-gastroenterology. Athens: H G E Update Medical Publ Ltd., v. 46, n. 26, p. 991-996, 1999.