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dc.contributor.authorMachado, Leonardo Martins [UNIFESP]
dc.contributor.authorCastro, Rosane S.
dc.contributor.authorFontes, Bruno Machado [UNIFESP]
dc.identifier.citationCornea. Philadelphia: Lippincott Williams & Wilkins, v. 28, n. 7, p. 732-734, 2009.
dc.description.abstractPurpose: To evaluate and compare conical staining patterns of lissamine green (LG) versus rose bengal (RB) in patients with dry eye syndrome. Secondary objectives included addressing patient's comfort after instillation and to correlate disease severity with staining patterns.Methods: Randomized, comparative, crossover series. Patients with previous diagnosis of mild to moderate dry eye syndrome were divided in 2 groups regarding dye instillation order (group A: RB first; group B: LG first). Both dyes were applied in regular intervals, and a staining score (van Bijsterveld scale) was used to correlate and compare the results. Disease severity was determined by the Ocular Surface Disease Index. Comfort was evaluated by patient's answer in an objective questionnaire.Results: Sixty eyes of 30 consecutive patients (24 females and 6 males) were included. There was no statistical difference between groups regarding disease severity, sex, or age. LG and RB showed good clinical correlation in both groups (group A: r = 0.939, P < 0.001; group B: r = 0.915, P < 0.001). LG was better tolerated than RB (P = 0.003 in both groups). Overall, We found a low statistical correlation between disease severity and staining scores.Conclusions: Both LG and RB showed similar staining patterns. RB was found to provide greater patient discomfort. There was no correlation between disease severity (addressed by the ocular surface disease index questionnaire) and staining patterns (measured by the van Bijsterveld scale).en
dc.publisherLippincott Williams & Wilkins
dc.rightsAcesso restrito
dc.subjectkeratoconjunctivitis siccaen
dc.subjectocular surfaceen
dc.subjectlissamine greenen
dc.subjectrose bengalen
dc.subjectdry eyeen
dc.titleStaining Patterns in Dry Eye Syndrome: Rose Bengal Versus Lissamine Greenen
dc.contributor.institutionUniversidade Estadual de Campinas (UNICAMP)
dc.contributor.institutionUniversidade Federal de São Paulo (UNIFESP)
dc.description.affiliationUniv Estadual Campinas, Dept Ophthalmol, Campinas, SP, Brazil
dc.description.affiliationUniv Fed Sao Paulo, Dept Ophthalmol, EPM, Sao Paulo, Brazil
dc.description.affiliationUnifespUniv Fed Sao Paulo, Dept Ophthalmol, EPM, Sao Paulo, Brazil
dc.description.sourceWeb of Science

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