Epiphyseal plate involvement in osteosarcoma
Jesus-Garcia, Reynaldo [UNIFESP]
Seixas, Maria Teresa de [UNIFESP]
Petrilli, Antonio Sergio [UNIFESP]
Laredo Filho, José [UNIFESP]
Is part ofClinical Orthopaedics And Related Research
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Fourteen boys (56%) and 11 girls (44%) 4 to 17 years of age (mean, 12.2 years) who had osteosarcoma and open epiphyseal plates were studied. A possible correlation between transepiphyseal spread of osteosarcoma and radiologic and histopathologic findings was investigated. Epiphyseal plate invasion aas detected radiologically in only 11 patients (44%), whereas histopathologic examination showed transepiphyseal extension in 21 patients (84%). The authors conclude that the epiphyseal plate is not a barrier against tumor growth and strongly recommend that limb salvage surgery preserving the epiphysis be planned carefully.
CitationClinical Orthopaedics And Related Research. Philadelphia: Lippincott Williams & Wilkins, n. 373, p. 32-38, 2000.
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