PARATHYROID-HORMONE SECRETORY RESERVE IN PATIENTS SUBMITTED TO 131-IODINE THERAPY FOR HYPERTHYROIDISM

Vieira, Jose Gilberto Henriques [UNIFESP]; Brandao, Cynthia Maria Alvares [UNIFESP]; Kasamatsu, Teresa Sayoko [UNIFESP]; Furlanetto, Reinaldo Perrone [UNIFESP]

PARATHYROID-HORMONE SECRETORY RESERVE IN PATIENTS SUBMITTED TO 131-IODINE THERAPY FOR HYPERTHYROIDISM

Data

1991-01-01

Autores

Vieira, Jose Gilberto Henriques

Brandao, Cynthia Maria Alvares

Kasamatsu, Teresa Sayoko

Furlanetto, Reinaldo Perrone

Tipo

Artigo

Resumo

Twelve euthyroid patients who had been treated with I-131 for hyperthyroidism due to Graves' disease and six normal controls were submitted to an EDTA infusion test. Ionized calcium and parathyroid hormone were measured in serum samples collected every 10 min during the 2-h test. Basal values for calcium (1.22 +/- 0.03 vs 1.23 +/- 0.03 pmol/l, mean +/- SD, controls vs patients) and parathyroid hormone (3.3 +/- 0.65 vs 5.1 +/- 2.32 pmol/l) as well as maximum response during infusion (1.01 +/- 0.04 vs 1.01 +/- 0.05 for calcium and 12.0 +/- 2.2 vs 13.1 +/- 3.7 for parathyroid hormone) were not significantly different. We conclude that I-131 treatment for hyperthyroidism due to Graves' disease had no effect on the parathyroid gland secretory reserve of the patients studied.

Citação

Brazilian Journal Of Medical And Biological Research. Sao Paulo: Assoc Bras Divulg Cientifica, v. 24, n. 11, p. 1103-1105, 1991.