High resolution manometric findings in patients with Chagas' disease esophagopathy

High resolution manometric findings in patients with Chagas' disease esophagopathy

Author Silva, Luciana Cristina Autor UNIFESP Google Scholar
Vicentine, Fernando Pompeu Piza Autor UNIFESP Google Scholar
Herbella, Fernando Augusto Mardiros Autor UNIFESP Google Scholar
Institution Universidade Federal de São Paulo (UNIFESP)
Abstract Objective: To describe high resolution manometry features of a population of symptomatic patients with Chagas' disease esophagopathy (EDE). Methods; Sixteen symptomatic dysphagic patients with EDE [mean age (54.81 +/- 13.43) years, 10 women] were included in this study. All patients underwent a high resolution manometry. Results; Mean lower esophageal sphincter (LES) extension was (3.02 +/- 1.17) cm with a mean basal pressure of (15.25 +/- 7.00) mmHg. Residual pressure was (14.31 +/- 9.19) mmHg. Aperistalsis was found in all 16 patients. Achalasia with minimal esophageal pressurization (type I) was present in 25% of patients and achalasia with esophageal compression (type 2) in 75%, according to the Chicago Classification. Upper esophageal sphincter (UES) mean brtsal pressure was (97.96 +/- 54.22) mmHg with a residual pressure of (12.95 +/- 6.42) mmHg. Conclusions: Our results show that LES was hypotensive or normotensive in the majority of the patients. Impaired relaxation was found in a minority of our patients. Aperistalsis was seen in 100% of patients. UES had impaired relaxation in a significant number of patients. Further clinical study is needed to investigate whether manometric features can predict outcomes following the studies of idiopathic achalasia..
Keywords Acahgaalass
Chagas disease
High resolution manometry
Language English
Date 2012-02-01
Published in Asian Pacific Journal Of Tropical Medicine. Oxford: Elsevier Sci Ltd, v. 5, n. 2, p. 110-112, 2012.
ISSN 1995-7645 (Sherpa/Romeo, impact factor)
Publisher Elsevier B.V.
Extent 110-112
Origin http://dx.doi.org/10.1016/S1995-7645(12)60006-6
Access rights Open access Open Access
Type Article
Web of Science ID WOS:000299265800006
URI http://repositorio.unifesp.br/11600/42767

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