Results of a prospective trial on elective modified radical classical versus supraomohyoid neck dissection in the management of oral squamous carcinoma

Results of a prospective trial on elective modified radical classical versus supraomohyoid neck dissection in the management of oral squamous carcinoma

Author Brentani, Ricardo Renzo Autor UNIFESP Google Scholar
Kowalski, Luiz Paulo Autor UNIFESP Google Scholar
Soares, Jose F. Google Scholar
Torloni, Humberto Google Scholar
Pereira, Raimunda N. Google Scholar
Ikeda, Mauro Kasuo Autor UNIFESP Google Scholar
Andrade, Roberto Paulo de Autor UNIFESP Google Scholar
Magrin, Jose Autor UNIFESP Google Scholar
Miguel, Roberto EV Google Scholar
Santos, Carlos R. Google Scholar
Saba, Leda MB Google Scholar
Salvajoli, João Victor Autor UNIFESP Google Scholar
Curado, Maria P. Google Scholar
Oliveira, Jose C. Google Scholar
Montandon, Paula O. Google Scholar
Machado, Marcio M. Google Scholar
Denofrio, Giovana F. Google Scholar
Quinta, Waldir C. Google Scholar
Alvarez, Rene B. Google Scholar
Alencar, Rita CG Google Scholar
Ferraz, Alberto R. Google Scholar
Brandao, Lenine Garcia Google Scholar
Cernea, Claudio Roberto Google Scholar
Santos, Luiz RM Google Scholar
Araujo, Virgilius Google Scholar
Antonangelo, Avelino Google Scholar
Silva, João LF Google Scholar
Della-Molle, Romuado Google Scholar
Feriancic, Carlos V. Google Scholar
Oliveira, Benedito V. Google Scholar
Ramos, Gil Google Scholar
Antunes, Lysandro S. Google Scholar
Andrade Sobrinho, Jose A. Google Scholar
Rapoport, Abrão Autor UNIFESP Google Scholar
Carvalho, Marcos B. Google Scholar
Fava, Antonio S. Google Scholar
Gois Filho, Jose Francisco de Autor UNIFESP Google Scholar
Chagas, José Francisco de Sales Autor UNIFESP Google Scholar
Kanda, Jossi Ledo Autor UNIFESP Google Scholar
Gripp, Flavio M. Google Scholar
Ribas, Marcelo H. Google Scholar
Castro, Ivan S. Google Scholar
Oliveira, Joni MS Google Scholar
Oliveira, José AM Google Scholar
Carvalho, Ricardo C. Google Scholar
Araujo, Lacerda B. Google Scholar
Pontes, Paulo AL Autor UNIFESP Google Scholar
Gregorio, Luiz C. Autor UNIFESP Google Scholar
Abrahão, Marcio Autor UNIFESP Google Scholar
Cervantes, Onivaldo Autor UNIFESP Google Scholar
Paiva, Marcos Bandiera Autor UNIFESP Google Scholar
Hebbel, Werner S. Autor UNIFESP Google Scholar
Fujita, Reginaldo Raimundo Autor UNIFESP Google Scholar
Motta, Pedro HH Autor UNIFESP Google Scholar
Segreto, Roberto Araujo Autor UNIFESP Google Scholar
Herter, Nilton T. Google Scholar
Mota, Neiro W. Google Scholar
Scholl, Joao G. Google Scholar
Kroef, Ricardo G. Google Scholar
Godoy, Paulo RF Google Scholar
Brazilian Head Neck Canc Study Grp Google Scholar
Institution Hosp AC Camargo
Ludwig Inst Canc Res
Hosp Araujo Jorge
Universidade de São Paulo (USP)
Hosp Erasto Gaertner
Hosp Heliopolis
Hosp Napoleao Laureano
Universidade Federal de São Paulo (UNIFESP)
Hosp Santa Rita
Abstract BACKGROUND: Elective treatment of the neck in oral squamous cell carcinoma has changed over the last 20 years. The main object of this report is to present the results of a multi-institutional prospective study designed to compare standard treatment with modified radical classical neck dissection (MRND) to supraomohyoid neck dissection (SOH) in the management of the clinically negative neck in oral cancer patients.PATIENTS AND METHODS: A total of 148 patients were included in the trial. All patients had previously untreated T2 to T4 NO squamous cell carcinoma of the oral tongue (62 cases), floor of the mouth (49 cases), inferior gingiva (12 cases), or retromolar trigone (25 cases). Tumor stages were T2, 91; T3, 27; and T4, 30. There were no significant imbalances between groups.RESULTS: The false-negative rate was 23%, and most positive nodes were sited at level II and III. Complications were seen in 41% of MRND patients and in 25% of SOH patients (P = 0.043). Median total duration of hospitalization was 9 days in MRND patients and 7 days in the SOH group. To date, 19 and 16 patients presented with local and neck recurrences, respectively. The 60-month actuarial survival rates were 63% in the MRND group and 67% in the SOH group (P = 0.7150).CONCLUSIONS: This study demonstrates that the recurrence and survival rates were similar in both groups. SOH neck dissection can be recommended as standard elective treatment for patients with T2-T4 oral squamous cell carcinomas. Am J Surg. 1998;176:422-427. (C) 1998 by Excerpta Medica, Inc.
Language English
Date 1998-11-01
Published in American Journal Of Surgery. New York: Cahners Publ Co, v. 176, n. 5, p. 422-427, 1998.
ISSN 0002-9610 (Sherpa/Romeo, impact factor)
Publisher Cahners Publ Co
Extent 422-427
Access rights Closed access
Type Article
Web of Science ID WOS:000077441400007

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