Persistent hyperactivity of the parathyroid glands in treated hypothyroid patients

Fecha
1990-12-01
Autor
Furlanetto, Reinaldo Perrone [UNIFESP]
Lazaretti-Castro, Marise [UNIFESP]
Kasamatsu, Teresa Sayoko [UNIFESP]
Brandao, Cynthia Maria Alvares [UNIFESP]
Vieira, Jose Gilberto Henriques [UNIFESP]
Tipo
Artigo
ISSN
0001-5598
Es parte de
Acta Endocrinologica
DOI
10.1530/acta.0.1230609
Metadatos
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Resumen
Twelve untreated hypothyroid patients were submitted to EDTA infusion and the parathyroid hormone response to the induced hypocalcemia was studied with an amino-terminal specific assay. Eight of these patients were retested 6 months after achieving clinical and laboratory euthyroidism. The PTH response in the pretreatment condition was significantly higher than that obtained in a group of 10 normal individuals; this increased response had not normalized after 6 months of euthyroidism. This persisting hyperresponsiveness can be a contributory factor to the bone hypersensitivity to thyroid hormone replacement seen in hypothyroid patients.
Cita
Acta Endocrinologica. Oslo: Scandinavian University Press, v. 123, n. 6, p. 609-612, 1990.
URI
http://repositorio.unifesp.br/11600/41995
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