Isolated trisomy 11 in de novo acute myeloid leukemia

Isolated trisomy 11 in de novo acute myeloid leukemia

Alternative title Trissomia 11 isolada em leucemia mielóide aguda de novo
Author Krum, Everson A. Autor UNIFESP Google Scholar
Hamed, Tatiane Autor UNIFESP Google Scholar
Yamamoto, Mihoko Autor UNIFESP Google Scholar
Chauffaille, Maria de Lourdes Lopes Ferrari Autor UNIFESP Google Scholar
Institution Universidade Federal de São Paulo (UNIFESP)
Abstract The real mechanism involved in trisomies and leukemogenesis remains unknown and more information about this connection is essential, but unfortunately the clinical outcome and hematological profile of patients with isolated trisomy 11 and AML have not been well characterized. Considering the limited data on the specific disease entity, the current report describes two cases of de novo acute monocytic leukemia (AMoL) and isolated +11, in which this event was further characterized.

O mecanismo envolvido em trissomias e leucemogênese permanece não esclarecido e mais dados sobre esta relação são fundamentais, mas infelizmente os resultados clínicos e o perfil hematológico dos pacientes com trissomia 11 isolada e LMA ainda não foram bem caracterizados. Considerando o limitado número de informações, este relato descreve dois casos de leucemia monocítica de novo e trissomia 11 onde este evento foi caracterizado.
Keywords Trisomy 11
acute myeloid leukemia
chromosomes
Trissomia 11
leucemia mielóide aguda
cromossomos
Language English
Date 2008-01-01
Published in Revista Brasileira de Hematologia e Hemoterapia. Associação Brasileira de Hematologia e Hemoterapia e Terapia Celular, v. 30, n. 3, p. 253-255, 2008.
ISSN 1516-8484 (Sherpa/Romeo)
Publisher Associação Brasileira de Hematologia e Hemoterapia e Terapia Celular
Extent 253-255
Origin http://dx.doi.org/10.1590/S1516-84842008000300016
Access rights Open access Open Access
Type Article
SciELO ID S1516-84842008000300016 (statistics in SciELO)
URI http://repositorio.unifesp.br/handle/11600/4138

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