Now showing items 1-20 of 112

    • Abnormalities in Metalloproteinase Pathways and IGF-I Axis: A Link Between Birth Weight, Hypertension, and Vascular Damage in Childhood 

      Sesso, Ricardo de Castro Cintra [UNIFESP]; Franco, Maria do Carmo Pinho [UNIFESP] (Nature Publishing Group, 2010-01-01)
      BACKGROUNDAlthough numerous studies suggest an inverse relationship between birth weight and cardiovascular disease, the mechanistic basis of this phenomenon is not fully understood. Here, we postulate that alterations in ...

      Souza, ERM; Boim, M. A.; Bergamaschi, C.; Versolato, C.; Pestana, JOM; Schor, N. [UNIFESP] (Elsevier B.V., 1992-12-01)
    • Acute effects of power and resistance exercises on hemodynamic measurements of older women 

      Coelho-Junior, Helio Jose; Irigoyen, Maria-Claudia; Aguiar, Samuel da Silva; Goncalves, Ivan de Oliveira; Saraiva Camara, Niels Olsen; Cenedeze, Marco Antonio [UNIFESP]; Asano, Ricardo Yukio; Rodrigues, Bruno; Uchida, Marco Carlos (Dove Medical Press Ltd, 2017)
      Purpose: The purpose of this study was to compare the acute effects of resistance training (RT) and power training (PT) on the hemodynamic parameters and nitric oxide (NO) bioavailability of older women. Materials and ...
    • Adequacy of Initial Everolimus Dose, With and Without Calcineurin Inhibitors, in Kidney Transplant Recipients 

      Felipe, Claudia [UNIFESP]; Ferreira, Alexandra [UNIFESP]; Bessa, Adrieli [UNIFESP]; Abait, Tamiris [UNIFESP]; Perez, Juliana D. [UNIFESP]; Casarini, Dulce Elena [UNIFESP]; Medina-Pestana, Jose [UNIFESP]; Tedesco, Helio [UNIFESP] (Lippincott Williams & Wilkins, 2018)
      Background: This study investigates the adequacy of initial everolimus (EVR) dose, with and without calcineurin inhibitors (CNI), in kidney transplant recipients. Methods: This retrospective cohort analysis involved data ...
    • The adipose tissue and the involvement of the renin-angiotensin-aldosterone system in cardiometabolic syndrome 

      Borghi, F.; Sevá-Pessôa, Bruno [UNIFESP]; Grassi-Kassisse, D. M. (Springer, 2016)
      Cardiometabolic diseases are linked to a cluster of modifiable factors, including risk factors closely related to central adiposity. Chronic renin-angiotensin-aldosterone system (RAAS) activation has far-reaching effects ...
    • Apolipoprotein E polymorphism modulation of asymmetric dimethylarginine in hypertensive patients is determined by renal function 

      Marrocos, Mauro Sergio Martins [UNIFESP]; Teixeira, Andrei Alkmin [UNIFESP]; Quinto, Beata Marie [UNIFESP]; Carmona, Silmara de Melo [UNIFESP]; Kuniyoshi, Mariana [UNIFESP]; Rodrigues, Cassio Jose [UNIFESP]; Dalboni, Maria Aparecida [UNIFESP]; Manfredi, Silvia [UNIFESP]; Canziani, Maria Eugenia [UNIFESP]; Batista, Marcelo Costa [UNIFESP] (Biomed Central Ltd, 2016)
      Background: Endothelial dysfunction is considered an early step of atherosclerotic vascular disease. Asymmetric dimethylarginine (ADMA), the main endogenous inhibitor of nitric oxide synthase (NOS), plays a critical role ...
    • Association of ACE Gene Insertion/Deletion Polymorphism With Birth Weight, Blood Pressure Levels, and ACE Activity in Healthy Children 

      Ajala, Aline Rodrigues [UNIFESP]; Almeida, Sandro Soares [UNIFESP]; Rangel, Marina [UNIFESP]; Palomino, Zaira [UNIFESP]; Strufaldi, Maria Wany Louzada [UNIFESP]; Puccini, Rosana Fiorini [UNIFESP]; Araújo, Ronaldo de Carvalho [UNIFESP]; Casarini, Dulce Elena [UNIFESP]; Franco, Maria do Carmo Pinho [UNIFESP] (Nature Publishing Group, 2012-07-01)
      BACKGROUNDThe human angiotensin-converting enzyme (ACE) gene contains a polymorphism consisting of either an insertion (I) or a deletion (D) of a 287 bp Alu repetitive sequence in intron 16. the potential role of ACE ...
    • Association of the PPP3CA c.249G>A variant with clinical outcomes of tacrolimus-based therapy in kidney transplant recipients 

      Salgado, Patricia C.; Genvigir, Fabiana D. V.; Felipe, Claudia Rosso [UNIFESP]; Tedesco-Silva Junior, Hélio [UNIFESP]; Pestana, Jose Osmar Medina [UNIFESP]; Doi, Sonia Q.; Hirata, Mario H.; Hirata, Rosario D. C. (Dove Medical Press Ltd, 2017)
      Background: The effects of genetic variants related to the pharmacodynamic mechanisms of immunosuppressive drugs on their therapeutic efficacy and safety have been poorly explored. This study was performed to investigate ...
    • Asymptomatic Ventricular Arrhythmia and Clinical Outcomes in Chronic Kidney Disease: A Pilot Study 

      Bonato, Fabiana Oliveira Bastos [UNIFESP]; Watanabe, Renato [UNIFESP]; Lemos, Marcelo Montebello [UNIFESP]; Cassiolato, Jose Luiz; Wolf, Myles; Canziani, Maria Eugênia Fernandes [UNIFESP] (Karger, 2017)
      Background/Aims: Ventricular arrhythmia is associated with increased risk of cardiovascular events and death in the general population. Sudden death is a leading cause of death in end-stage renal disease. We aimed at ...
    • Atenolol to Treat Intestinal Ischemia and Reperfusion in Rats 

      Campos, Viviane Ferreira [UNIFESP]; Miranda-Ferreira, Regiane [UNIFESP]; Taha, Nabiha Saadi Abrahão [UNIFESP]; Teixeira, G. D.; Souza, W. T. I.; Carmo, C. E. F.; Silva-Neto, L. A.; Gomes, I. T.; Monteiro, Hugo Pequeno; Montero, Edna Frasson de Souza; Fagundes, Djalma Jose [UNIFESP]; Caricati-Neto, Afonso; Taha, Murched Omar [UNIFESP] (Elsevier B.V., 2012-10-01)
      To study whether treatment with the beta-blocker atenolol (AT) attenuates intestinal dysfunction caused by ischemia (I) and reperfusion (R), rats were treated with AT (1.5 mg . kg(-1), intravenously) or saline solution ...
    • Avaliaçäo da eficácia, segurança e tolerabilidade do maleato de enalapril versus nifedipina no tratamento da hipertensäo arterial essencial leve e moderada 

      Plavnik, Frida Liane [UNIFESP]; Marson, Odair [UNIFESP]; Rodrigues, Cibele Isaac Saad [UNIFESP]; Neves, Francisco de Assis Rocha [UNIFESP]; Paula, Rogerio Baumgratz de [UNIFESP]; Kohlmann Junior, Osvaldo [UNIFESP]; Ribeiro, Artur Beltrame [UNIFESP] (Moreira Jr Editora Ltda, 1990-01-01)
    • Birth Weight and Its Relationship with the Cardiac Autonomic Balance in Healthy Children 

      Souza, Livia Victorino [UNIFESP]; Oliveira, Vanessa [UNIFESP]; Meneck, Franciele de [UNIFESP]; Clemente, Ana Paula Grotti; Strufaldi, Maria Wany Louzada [UNIFESP]; Franco, Maria do Carmo Pinho [UNIFESP] (Public Library Science, 2017)
      Several studies indicate that the fetal environment plays a significant role in the development of cardiometabolic disease later in life. However, a few studies present conflicting data about the correlation between birth ...
    • Bone turnover after bariatric surgery 

      Melo, Thalita Lima [UNIFESP]; Froeder, Leila [UNIFESP]; Baia, Leandro da Cunha [UNIFESP]; Heilberg, Ita Pfeferman [UNIFESP] (Sbem-Soc Brasil Endocrinologia & Metabologia, 2017)
      Objective: The aim of the present study was to evaluate parameters of bone and mineral metabolism after bariatric surgery. Subjects and methods: This sectional study included data from medical records from 61 bariatric ...

      Ramos, C. I. [UNIFESP]; Armani, R. G. [UNIFESP]; Canzianni, M. E. [UNIFESP]; Nakao, L. S.; Campbell, K. L.; Cuppari, L. [UNIFESP] (Wiley, 2017)
    • The burden of serious human fungal infections in Brazil 

      Giacomazzi, Juliana; Baethgen, Ludmila; Carneiro, Lilian C.; Millington, Maria Adelaide; Denning, David W.; Colombo, Arnaldo L. [UNIFESP]; Pasqualotto, Alessandro C. (Wiley-Blackwell, 2016)
      In Brazil, human fungal infections are prevalent, however, these conditions are not officially reportable diseases. To estimate the burden of serious fungal diseases in 1 year in Brazil, based on available data and published ...
    • Calcium oxalate crystals and oxalate induce an epithelial-to-mesenchymal transition in the proximal tubular epithelial cells: Contribution to oxalate kidney injury 

      Convento, Marcia Bastos [UNIFESP]; Pessoa, Edson Andrade [UNIFESP]; Cruz, Edgar [UNIFESP]; da Gloria, Maria Aparecida [UNIFESP]; Schor, Nestor [UNIFESP]; Borges, Fernanda Teixeira [UNIFESP] (Nature Publishing Group, 2017)
      TGF-beta 1 is the main mediator of epithelial-to-mesenchymal transition (EMT). Hyperoxaluria induces crystalluria, interstitial fibrosis, and progressive renal failure. This study analyzed whether hyperoxaluria is associated ...
    • Cardiac Autonomic Dysfunction in Offspring of Hypertensive Parents During Exercise 

      de Almeida, Leonardo Barbosa; Pecanha, Tiago; de Carvalho Mira, Pedro Augusto; de Souza, Livia Victorino [UNIFESP]; da Silva, Lilian Pinto; Martinez, Daniel Godoy; Guedes Freitas, Isabelle Magalhaes; Laterza, Mateus Camaroti (Georg Thieme Verlag Kg, 2017)
      Offspring of hypertensive parents present autonomic dysfunction at rest and during physiological maneuvers. However, the cardiac autonomic modulation during exercise remains unknown. This study tested whether the cardiac ...
    • Cholecalciferol decreases inflammation and improves vitamin D regulatory enzymes in lymphocytes in the uremic environment: A randomized controlled pilot trial 

      Carvalho, Jose Tarcisio G. [UNIFESP]; Schneider, Marion [UNIFESP]; Cuppari, Lilian [UNIFESP]; Grabulosa, Caren C. [UNIFESP]; Aoike, Danilo T. [UNIFESP]; Redublo, Beata Marie Q. [UNIFESP]; Batista, Marcelo C. [UNIFESP]; Cendoroglo, Miguel [UNIFESP]; Moyses, Rosa Maria; Dalboni, Maria Aparecida [UNIFESP] (Public Library Science, 2017)
      It has been reported that vitamin D regulates the immune system. However, whether vitamin D repletion modulates inflammatory responses in lymphocytes from dialysis patients is unclear. In the clinical trial, thirty-two ...
    • Circulating renin-angiotensin system and catecholamines in childhood: is there a role for birthweight? 

      Franco, Maria do Carmo Pinho [UNIFESP]; Casarini, Dulce Elena [UNIFESP]; Carneiro-Ramos, Marcella S.; Sawaya, Ana Lydia [UNIFESP]; Barreto-Chaves, Maria Luiza M.; Sesso, Ricardo de Castro Cintra [UNIFESP] (Portland Press Ltd, 2008-03-01)
      There have been only a few reports on the sympathoadrenal and renin-angiotensin systems in children of small gestational age. the purpose of the present study was to investigate plasma levels of ACE (angiotensin-converting ...
    • Clinical Presentation and Determinants of Mortality of Invasive Pulmonary Aspergillosis in Kidney Transplant Recipients: A Multinational Cohort Study 

      Lopez-Medrano, F.; Fernandez-Ruiz, M.; Silva, J. T.; Carver, P. L.; van Delden, C.; Merino, E.; Perez-Saez, M. J.; Montero, M.; Coussement, J.; Mazzolin, Milene de Abreu [UNIFESP]; Cervera, C.; Santos, L.; Sabe, N.; Scemla, A.; Cordero, E.; Cruzado-Vega, L.; Martin-Moreno, P. L.; Len, O.; Rudas, E.; de Leon, A. P.; Arriola, M.; Lauzurica, R.; David, M.; Gonzalez-Rico, C.; Henriquez-Palop, F.; Fortun, J.; Nucci, M.; Manuel, O.; Pano-Pardo, J. R.; Montejo, M.; Munoz, P.; Sanchez-Sobrino, B.; Mazuecos, A.; Pascual, J.; Horcajada, J. P.; Lecompte, T.; Moreno, A.; Carratala, J.; Blanes, M.; Hernandez, D.; Farinas, M. C.; Andres, A.; Aguado, J. M. (Wiley-Blackwell, 2016)
      The prognostic factors and optimal therapy for invasive pulmonary aspergillosis (IPA) after kidney transplantation (KT) remain poorly studied. We included in this multinational retrospective study 112 recipients diagnosed ...