Recent Submissions

  • Effects of transcutaneous electrical nerve stimulation on fetal and placental development in an experimental model of placental insufficiency 

    Guimaraes, Camila S. O.; Gomes, Bruno B. F.; Oliveira, Rafael A.; Yamamoto, Leandro R.; Rocha, Laura P.; Gloria, Maria A. [UNIFESP]; Machado, Juliana R.; Camara, Niels O. S. [UNIFESP]; Reis, Marlene A.; Correa, Rosana R. M. (Taylor & Francis Ltd, 2016)
    Objective: To elucidate the effects of transcutaneous electrical nerve stimulation (TENS) in pregnancies with placental insufficiency.Methods: Pregnant rats were subjected to uterine artery ligation and to TENS according ...
  • Treatment of patients with uric acid stones 

    Heilberg, Ita Pfeferman [UNIFESP] (Springer, 2016)
    Uric acid nephrolithiasis and unduly acidic urinary pH are both considered a renal manifestation of insulin resistance but the underlying mechanisms for the development of low urinary pH and the propensity for uric acid ...
  • Pharmacokinetics and Long-TermSafety and Tolerability of Everolimus in Renal Transplant Recipients Converted From Cyclosporine 

    Felipe, Claudia R. [UNIFESP]; Oliveira, Nagilla I. [UNIFESP]; Hannun, Pedro G. [UNIFESP]; de Paula, Mayara Ivani [UNIFESP]; Tedesco-Silva, Helio [UNIFESP]; Medina-Pestana, Jose O. [UNIFESP] (Lippincott Williams & Wilkins, 2016)
    Background:Conversion from cyclosporine (CsA) to everolimus (EVR) in kidney transplant recipients receiving mycophenolate sodium (MPS) and corticosteroids has been used to reduce CsA associated toxicities. Nevertheless, ...
  • Time-Dependent and Immunosuppressive Drug-Associated Adverse Event Profiles in De Novo Kidney Transplant Recipients Converted from Tacrolimus to Sirolimus Regimens 

    Felix, Maria Julia Pereira [UNIFESP]; Felipe, Claudia Rosso [UNIFESP]; Tedesco-Silva, Helio [UNIFESP]; Medina-Pestana, Jose Osmar [UNIFESP] (Wiley-Blackwell, 2016)
    Study ObjectiveTo evaluate the safety and tolerability of immunosuppressive drugs used in a planned randomized conversion from a calcineurin inhibitor, tacrolimus, to a mammalian target of rapamycin inhibitor, sirolimus, ...
  • Effects of transcutaneous electrical nerve stimulation on fetal and placental development in an experimental model of placental insufficiency 

    Guimaraes, Camila S. O.; Gomes, Bruno B. F.; Oliveira, Rafael A.; Yamamoto, Leandro R.; Rocha, Laura P.; Gloria, Maria A. [UNIFESP]; Machado, Juliana R.; Camara, Niels O. S. [UNIFESP]; Reis, Marlene A.; Correa, Rosana R. M. (Taylor & Francis Ltd, 2016)
    Objective: To elucidate the effects of transcutaneous electrical nerve stimulation (TENS) in pregnancies with placental insufficiency.Methods: Pregnant rats were subjected to uterine artery ligation and to TENS according ...
  • Apolipoprotein E polymorphism modulation of asymmetric dimethylarginine in hypertensive patients is determined by renal function 

    Marrocos, Mauro Sergio Martins [UNIFESP]; Teixeira, Andrei Alkmin [UNIFESP]; Quinto, Beata Marie [UNIFESP]; Carmona, Silmara de Melo [UNIFESP]; Kuniyoshi, Mariana [UNIFESP]; Rodrigues, Cassio Jose [UNIFESP]; Dalboni, Maria Aparecida [UNIFESP]; Manfredi, Silvia [UNIFESP]; Canziani, Maria Eugenia [UNIFESP]; Batista, Marcelo Costa [UNIFESP] (Biomed Central Ltd, 2016)
    Background: Endothelial dysfunction is considered an early step of atherosclerotic vascular disease. Asymmetric dimethylarginine (ADMA), the main endogenous inhibitor of nitric oxide synthase (NOS), plays a critical role ...
  • Treatment of patients with uric acid stones 

    Heilberg, Ita Pfeferman [UNIFESP] (Springer, 2016)
    Uric acid nephrolithiasis and unduly acidic urinary pH are both considered a renal manifestation of insulin resistance but the underlying mechanisms for the development of low urinary pH and the propensity for uric acid ...
  • Pharmacokinetics and Long-TermSafety and Tolerability of Everolimus in Renal Transplant Recipients Converted From Cyclosporine 

    Felipe, Claudia R. [UNIFESP]; Oliveira, Nagilla I. [UNIFESP]; Hannun, Pedro G. [UNIFESP]; de Paula, Mayara Ivani [UNIFESP]; Tedesco-Silva, Helio [UNIFESP]; Medina-Pestana, Jose O. [UNIFESP] (Lippincott Williams & Wilkins, 2016)
    Background:Conversion from cyclosporine (CsA) to everolimus (EVR) in kidney transplant recipients receiving mycophenolate sodium (MPS) and corticosteroids has been used to reduce CsA associated toxicities. Nevertheless, ...
  • Time-Dependent and Immunosuppressive Drug-Associated Adverse Event Profiles in De Novo Kidney Transplant Recipients Converted from Tacrolimus to Sirolimus Regimens 

    Felix, Maria Julia Pereira [UNIFESP]; Felipe, Claudia Rosso [UNIFESP]; Tedesco-Silva, Helio [UNIFESP]; Medina-Pestana, Jose Osmar [UNIFESP] (Wiley-Blackwell, 2016)
    Study ObjectiveTo evaluate the safety and tolerability of immunosuppressive drugs used in a planned randomized conversion from a calcineurin inhibitor, tacrolimus, to a mammalian target of rapamycin inhibitor, sirolimus, ...
  • Nutritional assessment of elderly patients on dialysis: pitfalls and potentials for practice 

    Rodrigues, Juliana; Cuppari, Lilian [UNIFESP]; Campbell, Katrina L.; Avesani, Carla Maria (Oxford Univ Press, 2017)
    The chronic kidney disease (CKD) population is aging. Currently a high percentage of patients treated on dialysis are older than 65 years. As patients get older, several conditions contribute to the development of malnutrition, ...
  • Efficacy of Prolonged- and Immediate-release Tacrolimus in Kidney Transplantation: A Pooled Analysis of Two Large, Randomized, Controlled Trials 

    Kraemer, B. K.; Albano, L.; Banas, B.; Charpentier, B.; Backman, L.; Tedesco-Silva, H., Jr. [UNIFESP]; Lehner, F.; Mondragon-Ramirez, G. A.; Glyda, M.; Cassuto-Viguier, E.; Viklicky, O.; Mourad, G.; Rigotti, P.; Schleibner, S.; Kamar, N. (Elsevier Science Inc, 2017)
    Background. Two large, prospective studies (12-03; OSAKA) compared the efficacy and tolerability of prolonged-release versus immediate-release tacrolimus in kidney transplant patients also receiving mycophenolate mofetil ...
  • Effect of Omega-3 Fatty Acid Supplementation on Plasma Fibroblast Growth Factor 23 Levels in Post-Myocardial Infarction Patients with Chronic Kidney Disease: The Alpha Omega Trial 

    de Borst, Martin H.; Baia, Leandro C. [UNIFESP]; Hoogeveen, Ellen K.; Giltay, Erik J.; Navis, Gerjan; Bakker, Stephan J. L.; Geleijnse, Johanna M.; Kromhout, Daan; Soedamah-Muthu, Sabita S. (Mdpi Ag, 2017)
    Fibroblast growth factor 23 (FGF23) is an independent risk factor for cardiovascular mortality in chronic kidney disease. Omega-3 (n-3) fatty acid consumption has been inversely associated with FGF23 levels and with ...
  • Intrauterine growth restriction-induced deleterious adaptations in endothelial progenitor cells: possible mechanism to impair endothelial function 

    Oliveira, Vanessa [UNIFESP]; Souza, Livia Victorino de [UNIFESP]; Fernandes, Tiago; Silva Júnior, Sebastião Donato; Carvalho, Maria Helena Catelli de; Akamine, Eliana Hiromi; Michelini, Lisete Compagno; Oliveira, Edilamar Menezes de; Franco, Maria do Carmo Pinho [UNIFESP] (Cambridge Univ Press, 2017)
    Intrauterine growth restriction (IUGR) can induce deleterious changes in the modulatory ability of the vascular endothelium, contributing to an increased risk of developing cardiovascular diseases in the long term. However, ...
  • Hyperoxaluria in a Model of Mini-Gastric Bypass Surgery in Rats 

    Ormanji, Milene S. [UNIFESP]; Korkes, Fernando [UNIFESP]; Meca, Renata [UNIFESP]; Ishiy, Crysthiane S. R. A. [UNIFESP]; Finotti, Gustavo H. C. [UNIFESP]; Ferraz, Renato R. N. [UNIFESP]; Heilberg, Ita P. [UNIFESP] (Springer, 2017)
    Bariatric surgery is associated with hyperoxaluria hence predisposing to nephrolithiasis. The present study aimed to investigate the underlying mechanisms contributing to increased urinary oxalate in a mini-gastric bypass ...
  • Cardiac Autonomic Dysfunction in Offspring of Hypertensive Parents During Exercise 

    de Almeida, Leonardo Barbosa; Pecanha, Tiago; de Carvalho Mira, Pedro Augusto; de Souza, Livia Victorino [UNIFESP]; da Silva, Lilian Pinto; Martinez, Daniel Godoy; Guedes Freitas, Isabelle Magalhaes; Laterza, Mateus Camaroti (Georg Thieme Verlag Kg, 2017)
    Offspring of hypertensive parents present autonomic dysfunction at rest and during physiological maneuvers. However, the cardiac autonomic modulation during exercise remains unknown. This study tested whether the cardiac ...
  • Innate Sensing of the Gut Microbiota: Modulation of Inflammatory and Autoimmune Diseases 

    Ignacio, Aline; Morales, Camila Ideli; Saraiva Camara, Niels Olsen [UNIFESP]; Almeida, Rafael Ribeiro (Frontiers Media Sa, 2016)
    The mammalian gastrointestinal tract harbors a diverse microbial community with which dynamic interactions have been established over millennia of coevolution. Commensal bacteria and their products are sensed by innate ...
  • The burden of serious human fungal infections in Brazil 

    Giacomazzi, Juliana; Baethgen, Ludmila; Carneiro, Lilian C.; Millington, Maria Adelaide; Denning, David W.; Colombo, Arnaldo L. [UNIFESP]; Pasqualotto, Alessandro C. (Wiley-Blackwell, 2016)
    In Brazil, human fungal infections are prevalent, however, these conditions are not officially reportable diseases. To estimate the burden of serious fungal diseases in 1 year in Brazil, based on available data and published ...
  • Sensitivity and Specificity of Body Mass Index as a Marker of Obesity in Elderly Patients on Hemodialysis 

    Rodrigues, Juliana; Santin, Fernanda; Barbosa Brito, Flavia Santos; Carrero, Juan Jesus; Lindholm, Bengt; Cuppari, Lilian [UNIFESP]; Avesani, Carla Maria (W B Saunders Co-Elsevier Inc, 2016)
    Objectives: Diagnosing obesity by body mass index (BMI) may not be reliable in elderly individuals due to the changes in body composition. We aimed to analyze the accuracy of BMI thresholds by World Health Organization ...
  • Screening for muscle wasting and dysfunction in patients with chronic kidney disease 

    Carrero, Juan J.; Johansen, Kirsten L.; Lindholm, Bengt; Stenvinkel, Peter; Cuppari, Lilian [UNIFESP]; Avesani, Carla M. (Nature Publishing Group, 2016)
    Skeletal muscle mass and muscle function are negatively affected by a variety of conditions inherent to chronic kidney disease (CKD) and to dialysis treatment. Skeletal muscle mass and function serve as indicators of the ...
  • Risk Factors Associated With Early Invasive Pulmonary Aspergillosis in Kidney Transplant Recipients: Results From a Multinational Matched Case-Control Study 

    Lopez-Medrano, F.; Silva, J. T.; Fernandez-Ruiz, M.; Carver, P. L.; van Delden, C.; Merino, E.; Perez-Saez, M. J.; Montero, M.; Coussement, J.; de Abreu Mazzolin, M. [UNIFESP]; Cervera, C.; Santos, L.; Sabe, N.; Scemla, A.; Cordero, E.; Cruzado-Vega, L.; Martin-Moreno, P. L.; Len, O.; Rudas, E.; Ponce de Leon, A.; Arriola, M.; Lauzurica, R.; David, M.; Gonzalez-Rico, C.; Henriquez-Palop, F.; Fortun, J.; Nucci, M.; Manuel, O.; Pano-Pardo, J. R.; Montejo, M.; Munoz, P.; Sanchez-Sobrino, B.; Mazuecos, A.; Pascual, J.; Horcajada, J. P.; Lecompte, T.; Lumbreras, C.; Moreno, A.; Carratala, J.; Blanes, M.; Hernandez, D.; Hernandez-Mendez, E. A.; Farinas, M. C.; Perello-Carrascosa, M.; Morales, J. M.; Andres, A.; Aguado, J. M. (Wiley-Blackwell, 2016)
    Risk factors for invasive pulmonary aspergillosis (IPA) after kidney transplantation have been poorly explored. We performed a multinational case-control study that included 51 kidney transplant (KT) recipients diagnosed ...

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