Lupus in Latin-American patients: lessons from the GLADEL cohort

Lupus in Latin-American patients: lessons from the GLADEL cohort

Author Pons-Estel, G. J. Google Scholar
Catoggio, L. J. Google Scholar
Cardiel, M. H. Google Scholar
Bonfa, E. Google Scholar
Caeiro, F. Google Scholar
Sato, E. Autor UNIFESP Google Scholar
Massardo, L. Google Scholar
Molina-Restrepo, J. F. Google Scholar
Guibert Toledano, M. Google Scholar
Barile-Fabris, L. A. Google Scholar
Amigo, M. C. Google Scholar
Acevedo-Vasquez, E. M. Google Scholar
Abadi, Isaac Google Scholar
Wojdyla, D. Google Scholar
Alarcon-Riquelme, M. E. Google Scholar
Alarcon, G. S. Google Scholar
Pons-Estel, B. A. Google Scholar
GLADEL Google Scholar
Institution Hosp Clin Barcelona
Hosp Italiano Buenos Aires
Fdn Dr Pedro M Catoggio Progreso Reumatol
Ctr Invest Clin Morelia SC
Universidade de São Paulo (USP)
Ctr Med Cordoba
Universidade Federal de São Paulo (UNIFESP)
Pontificia Univ Catolica Chile
Univ CES
Ctr Invest Med Quirurg CIMEQ
Inst Mexicano Seguro Social
Ctr Med ABC
Hosp Nacl Guillermo Almenara Irigoyen
Hosp Clin
Univ Nacl Rosario
Univ Granada
Oklahoma Med Res Fdn
Univ Alabama Birmingham
Hosp Prov Rosario
Abstract The need for comprehensive published epidemiologic and clinical data from Latin American systemic lupus erythematosus (SLE) patients motivated the late Dr Alarcon-Segovia and other Latin American professionals taking care of these patients to spearhead the creation of the Grupo Latino Americano de Estudio del Lupus (GLADEL) cohort in 1997. This inception cohort recruited a total of 1480 multiethnic (Mestizo, African-Latin American (ALA), Caucasian and other) SLE patients diagnosed within two years from the time of enrollment from 34 Latin American centers with expertise in the diagnosis and management of this disease. in addition to the initial 2004 description of the cohort, GLADEL has contributed to improving our knowledge about the course and outcome of lupus in patients from this part of the Americas. the major findings from this cohort are highlighted in this review. They have had important clinical implications for the adequate care of SLE patients both in Latin America and worldwide where these patients may have emigrated.
Keywords Systemic lupus erythematosus
renal lupus
cardiovascular disease
Language English
Sponsor Federico Wilhelm Agricola Foundation Research
Supporting Training Efforts in Lupus for Latin-American Rheumatologists (STELLAR) Program - Rheuminations Inc
Institut d'Investigacions Biomediques August Pi i Sunyer (IDIBAPS)-Beca de Formacio i Contractacio de Personal Investigador
Date 2015-05-01
Published in Lupus. London: Sage Publications Ltd, v. 24, n. 6, p. 536-545, 2015.
ISSN 0961-2033 (Sherpa/Romeo, impact factor)
Publisher Sage Publications Ltd
Extent 536-545
Access rights Closed access
Type Review
Web of Science ID WOS:000353586100002

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