Show simple item record

dc.contributor.authorCamargo, L. F. A. [UNIFESP]
dc.contributor.authorMarra, A. R. [UNIFESP]
dc.contributor.authorPignatari, A. C. C. [UNIFESP]
dc.contributor.authorSukiennik, T.
dc.contributor.authorBehar, P. P. P.
dc.contributor.authorMedeiros, E. A. S. [UNIFESP]
dc.contributor.authorRibeiro, J.
dc.contributor.authorGirao, E.
dc.contributor.authorCorrea, L.
dc.contributor.authorGuerra, C.
dc.contributor.authorBrites, C.
dc.contributor.authorPereira, C. A. P.
dc.contributor.authorCarneiro, I.
dc.contributor.authorReis, M.
dc.contributor.authorSouza, M. A.
dc.contributor.authorBarata, C. U.
dc.contributor.authorEdmond, M. B.
dc.contributor.authorBrazilian SCOPE Study Grp
dc.identifier.citationTransplant Infectious Disease. Hoboken: Wiley-Blackwell, v. 17, n. 2, p. 308-313, 2015.
dc.description.abstractBackgroundThe incidence of bloodstream infection (BSI) varies according to the transplanted organ. Mortality can be as high as 24%, with a significant impact on graft survival. Transplantation is a risk factor for multidrug-resistant (MDR) organisms, but comparison with a non-transplanted population in a single large cohort has not been described.MethodsThis is a prospective nationwide study (16 centers) reporting data on 2364 monomicrobial nosocomial BSIs, comparing 83 episodes in solid organ transplant patients with 2447 BSIs occurring in the general hospital population.ResultsThe prevalence of groups of infecting organisms (gram-positive, gram-negative, and fungi) was similar between transplant patients and the general population and a similar crude mortality rate was observed (34.9% in transplant vs. 43.3% in non-transplant patients). Staphylococcus aureus was the single most frequently isolated organism in both groups, and Acinetobacter species was more frequently isolated in the general population. Regarding MDR organisms, Klebsiella species, and Enterobacter species resistant to cefepime, as well as Acinetobacter species resistant to meropenem, were significantly more frequent in transplant patients.ConclusionAntimicrobial resistance is higher, particularly among gram-negative bacteria in the transplant population, although the overall mortality rate between transplant and non-transplant patients with nosocomial BSI is similar.en
dc.description.sponsorshipPfizer Laboratories
dc.description.sponsorshipFundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)
dc.relation.ispartofTransplant Infectious Disease
dc.rightsAcesso restrito
dc.subjectbloodstream infectionen
dc.titleNosocomial bloodstream infections in a nationwide study: comparison between solid organ transplant patients and the general populationen
dc.contributor.institutionHosp Israelita Albert Einstein
dc.contributor.institutionUniversidade Federal de São Paulo (UNIFESP)
dc.contributor.institutionHosp 9 Julho
dc.contributor.institutionSanta Casa Porto Alegre
dc.contributor.institutionHosp Conceicao
dc.contributor.institutionHosp Base
dc.contributor.institutionHosp Walter Cantidio
dc.contributor.institutionHosp Rim & Hipertensao
dc.contributor.institutionHosp Diadema
dc.contributor.institutionHosp Espanhol
dc.contributor.institutionInst Oncol Pediat IOP GRAAC
dc.contributor.institutionHosp Coracao
dc.contributor.institutionHosp UNIMED
dc.contributor.institutionHosp Clin Goiania
dc.contributor.institutionUniv Fed Triangulo Mineiro
dc.contributor.institutionVirginia Commonwealth Univ
dc.description.affiliationHosp Israelita Albert Einstein, São Paulo, Brazil
dc.description.affiliationUniversidade Federal de São Paulo UNIFESP, São Paulo, Brazil
dc.description.affiliationHosp 9 Julho, São Paulo, Brazil
dc.description.affiliationSanta Casa Porto Alegre, Porto Alegre, RS, Brazil
dc.description.affiliationHosp Conceicao, Porto Alegre, RS, Brazil
dc.description.affiliationHosp Base, Brasilia, DF, Brazil
dc.description.affiliationHosp Walter Cantidio, Fortaleza, Ceara, Brazil
dc.description.affiliationHosp Rim & Hipertensao, São Paulo, Brazil
dc.description.affiliationHosp Diadema, São Paulo, Brazil
dc.description.affiliationHosp Espanhol, Salvador, BA, Brazil
dc.description.affiliationInst Oncol Pediat IOP GRAAC, São Paulo, Brazil
dc.description.affiliationHosp Coracao, Natal, RN, Brazil
dc.description.affiliationHosp UNIMED, Natal, RN, Brazil
dc.description.affiliationHosp Clin Goiania, Goiania, Go, Brazil
dc.description.affiliationUniv Fed Triangulo Mineiro, Uberaba, MG, Brazil
dc.description.affiliationVirginia Commonwealth Univ, Richmond, VA USA
dc.description.affiliationUnifespUniversidade Federal de São Paulo UNIFESP, EPM, São Paulo, Brazil
dc.description.sourceWeb of Science

Files in this item


There are no files associated with this item.

This item appears in the following Collection(s)

Show simple item record