Low-dose radiation protocol using 3D mode in a BGO PET/CT

Low-dose radiation protocol using 3D mode in a BGO PET/CT

Author Nogueira, Solange A. Autor UNIFESP Google Scholar
Dimenstein, Renato Google Scholar
Cunha, Marcelo L. Google Scholar
Wagner, Jairo Google Scholar
Funari, Marcelo B. G. Google Scholar
Lederman, Henrique M. Autor UNIFESP Google Scholar
Institution Hosp Israelita Albert Einstein
Universidade Federal de São Paulo (UNIFESP)
Abstract The use of positron emission tomography combined with computed tomography (PET/CT) has brought about significant technological advancement in diagnostic imaging, and a number of PET/CT scanners with bismuth germanate detectors can perform imaging in both 2D and 3D acquisition modes. Nevertheless, certain image acquisition parameters and physical features of patients have to be considered when designing low-dose protocols in the 3D mode.The aim of this study was to compare images acquired in 2D and 3D modes and establish a low-dose protocol for use in PET/CT imaging, decreasing patient exposure to radiation without compromising results.A total of 30 patients, aged 4-72 years, participated in this prospective study, which was conducted at Albert Einstein Hospital, So Paulo, Brazil. Images were evaluated for picture quality, presence/absence of lesions and the number of lesions that were detectable in both acquisition modes.The results consistently showed that the loss in image quality in the 3D mode did not affect exam interpretation and lesion detection when compared with 2D at higher dose and for a longer time.We therefore conclude that administration of 3.7 MBq [F-18]-fluorodeoxyglucose (FDG)/kg for an acquisition time of 3 min per FOV (field of view) is optimal for image acquisition in the 3D mode. This protocol, which reduces the acquisition time and radiation dose, is quite beneficial, especially for children.
Keywords F-18-FDG
Dose reduction
Language English
Sponsor Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)
Date 2015-02-01
Published in Radiologia Medica. Milan: Springer-verlag Italia Srl, v. 120, n. 2, p. 251-255, 2015.
ISSN 0033-8362 (Sherpa/Romeo, impact factor)
Publisher Springer
Extent 251-255
Origin http://dx.doi.org/10.1007/s11547-014-0422-z
Access rights Closed access
Type Article
Web of Science ID WOS:000349910500009
URI http://repositorio.unifesp.br/handle/11600/38683

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