Gene-therapy for malaria prevention

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Data
2014-11-01
Autores
Rodrigues, Mauricio M. [UNIFESP]
Soares, Irene S.
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Editorial
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Resumo
The limited number of tools for malaria prevention and the inability to eradicate the disease have required large investments in vaccine development, as vaccines have been the only foreseeable type of immunoprophylaxis against malaria. An alternative strategy named vectored immunoprophylaxis (VIP) now would allow genetically transduced host cells to assemble and secrete antibodies that neutralize the infectivity of the malaria parasite and prevent disease.
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Citação
Trends in Parasitology. Oxford: Elsevier B.V., v. 30, n. 11, p. 511-513, 2014.