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dc.contributor.authorFerreira, Guilherme S.
dc.contributor.authorMoreira, Carolina R. L.
dc.contributor.authorKleinman, Ana
dc.contributor.authorNader, Edmir C. G. P.
dc.contributor.authorGomes, Bernardo Carramao
dc.contributor.authorTeixeira, Ana Maria A.
dc.contributor.authorAlmeida Rocca, Cristiana C.
dc.contributor.authorNicoletti, Mark
dc.contributor.authorSoares, Jair C.
dc.contributor.authorBusatto, Geraldo F.
dc.contributor.authorLafer, Beny
dc.contributor.authorCaetano, Sheila C.
dc.identifier.citationAustralian and New Zealand Journal of Psychiatry. London: Sage Publications Ltd, v. 47, n. 11, p. 1051-1057, 2013.
dc.description.abstractObjective: Children of parents with bipolar disorder (BD) are at heightened risk for developing mood and other psychiatric disorders. We proposed to evaluate the environment of families with at least one parent with BD type I (BDF) with affected offspring (aBDF) and unaffected offspring (uBDF) compared with control families without a history of DSM-IV Axis I disorder (CF).Method: We used the Family Environment Scale (FES) to evaluate 47 BDF (aBDF + uBDF) and 30 CF. Parents were assessed through the Structured Clinical Interview for DSM-IV Axis I Disorders (SCID-I). Diagnosis of the offspring was determined through the Schedule for Affective Disorders and Schizophrenia for School-Age Children/Present and Lifetime Version (K-SADS-PL) interview.Results: There were statistically significant differences between aBDF, uBDF and CF in cohesion (p = 0.003), intellectual-cultural orientation (p = 0.01), active-recreational orientation (p = 0.007), conflict (p = 0.001), control (p = 0.01), moral-religious emphasis (p = 0.01) and organization (p = 0.001). the aBDF showed higher levels of control (p = 0.02) when compared to the uBDF.Conclusions: Families with a BD parent presented more dysfunctional interactions among members. Moreover, the presence of BD or other psychiatric disorders in the offspring of parents with BD is associated with higher levels of control. These results highlight the relevance of psychosocial interventions to improve resilience and family interactions.en
dc.description.sponsorshipFundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)
dc.description.sponsorshipConselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)
dc.description.sponsorshipNational Alliance for Research on Schizophrenia and Depression (NARSAD)
dc.description.sponsorshipAmerican Psychiatric Association/AstraZeneca Young Minds in Psychiatry International Awards
dc.description.sponsorshipL'Oreal-ABC-Unesco - Para Mulheres na Ciencia, Brazil.
dc.publisherSage Publications Ltd
dc.relation.ispartofAustralian and New Zealand Journal of Psychiatry
dc.rightsAcesso restrito
dc.subjectbipolar disorderen
dc.subjectfamily environmenten
dc.titleDysfunctional family environment in affected versus unaffected offspring of parents with bipolar disorderen
dc.contributor.institutionUniversidade de São Paulo (USP)
dc.contributor.institutionUniv Texas Med Sch
dc.contributor.institutionUniversidade Federal de São Paulo (UNIFESP)
dc.description.affiliationUniv São Paulo, Sch Med, Dept Psychiat, Bipolar Res Program, São Paulo, Brazil
dc.description.affiliationUniv São Paulo, Sch Med, Dept Psychiat, Lab Psychiat Neuroimaging LIM 21, São Paulo, Brazil
dc.description.affiliationUniv São Paulo, Ctr Support Res Appl Neurosci, NAPNA, São Paulo, Brazil
dc.description.affiliationUniv Texas Med Sch, Dept Psychiat & Behav Sci, Houston, TX USA
dc.description.affiliationFed Univ São Paulo UNIFESP, Dept Psychiat, Child & Adolescent Psychiat Unit UPIA, São Paulo, Brazil
dc.description.affiliationUnifespFed Univ São Paulo UNIFESP, Dept Psychiat, Child & Adolescent Psychiat Unit UPIA, São Paulo, Brazil
dc.description.sourceWeb of Science

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