Chemical constituents derived from Drimys brasiliensis Miers (Winteraceae)
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2013-10-01
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Mecchi, Murillo C. [UNIFESP]
Lago, Joao Henrique G. [UNIFESP]
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Phytochemical investigation on Drimys brasiliensis afforded the isolation and characterisation of four drimane sesquiterpenes: polygodial (1), warburganal (2), 1--(p-coumaroyloxy)polygodial (3) and 1--(p-methoxycinnamoyl)polygodial (4), as well as four flavonoids: quercitrin (5), astilbin (6), isoastilbin (7) and neoastilbin (8). the structures were elucidated on the basis of their spectral data and compared with those reported in the literature. Compounds 2, 5-8 have been reported to occur for the first time in D. brasiliensis, while compounds 5, 7 and 8 have been reported to occur for the first time in the genus Drimys. the chemotaxonomic significance of these compounds, mainly flavonoids 5-8 in D. brasiliensis, was summarised.
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Natural Product Research. Abingdon: Taylor & Francis Ltd, v. 27, n. 20, p. 1927-1929, 2013.