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dc.contributor.authorFragoso, Yara Dadalti
dc.contributor.authorAdoni, Tarso
dc.contributor.authorBichuetti, Denis Bernardi [UNIFESP]
dc.contributor.authorBidin Brooks, Joseph Bruno
dc.contributor.authorBrito Ferreira, Maria Lucia
dc.contributor.authorLobato Oliveira, Enedina Maria [UNIFESP]
dc.contributor.authorSilva Oliveira, Celso Luis
dc.contributor.authorFelix Ribeiro, Sonia Beatriz
dc.contributor.authorSilva, Alex Eduardo
dc.contributor.authorSiquineli, Fabio
dc.identifier.citationJournal of Neurology. Heidelberg: Springer Heidelberg, v. 260, n. 10, p. 2614-2619, 2013.
dc.description.abstractLess than a hundred cases of pregnancies in women with neuromyelitis optica (NMO) have been published in the world. the aim of the present study was to add the Brazilian experience to this subject. Cases of women with NMO who became pregnant, or who developed NMO soon after pregnancy, were included. Retrospective analysis of medical data from these patients was carried out by the neurologist responsible for the case. Seventeen cases of pregnancies (16 full-term pregnancies, one miscarriage) were identified. the relapse rate of demyelinating events in the first trimester after pregnancy was significantly higher than at any other time. Disability progression was significantly worse 1 year after delivery. Pregnancy negatively influenced the disease course of NMO in these women. These results are similar to those of other authors, although the total number of cases so far described is still small. Obstetricians must be aware of the potential complications of a pregnancy in a woman who has NMO.en
dc.relation.ispartofJournal of Neurology
dc.rightsAcesso restrito
dc.subjectNeuromyelitis opticaen
dc.subjectDevic's diseaseen
dc.titleNeuromyelitis optica and pregnancyen
dc.contributor.institutionUniv Metropolitana Santos UNIMES
dc.contributor.institutionHosp Sirio Libanes
dc.contributor.institutionUniversidade Federal de São Paulo (UNIFESP)
dc.contributor.institutionHosp Restauracao
dc.contributor.institutionUniv Fed Triangulo Mineiro
dc.contributor.institutionUniv Reg Blumenau
dc.description.affiliationUniv Metropolitana Santos UNIMES, Dept Neurol, Sch Med, BR-11015470 Santos, SP, Brazil
dc.description.affiliationHosp Sirio Libanes, Dept Neurol, São Paulo, Brazil
dc.description.affiliationUniversidade Federal de São Paulo, Discipline Neurol, São Paulo, Brazil
dc.description.affiliationHosp Restauracao, Demyelinating Dis Unit, Recife, PE, Brazil
dc.description.affiliationUniv Fed Triangulo Mineiro, Dept Neurol, Uberaba, MG, Brazil
dc.description.affiliationUniv Reg Blumenau, Dept Neurol, Blumenau, SC, Brazil
dc.description.affiliationUnifespUniversidade Federal de São Paulo, Discipline Neurol, São Paulo, Brazil
dc.description.sourceWeb of Science

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