First Description of KPC-2-Producing Klebsiella oxytoca in Brazil

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Date
2013-08-01
Author
Almeida, Anna C. S.
Cavalcanti, Felipe L. S.
Martins, Willames M. B.
Vilela, Marinalda A.
Gales, Ana C. [UNIFESP]
Morais Junior, Marcos A.
Morais, Marcia M. C.
Type
Artigo
ISSN
0066-4804
Is part of
Antimicrobial Agents and Chemotherapy
DOI
10.1128/AAC.02376-12
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Abstract
The present work reports the detection of the first case of nosocomial Klebsiella oxytoca producing class A carbapenemase KPC-2 in Brazil. the isolate KPN106 carried a 65-kb IncW-type plasmid that harbors the bla(KPC) gene and Tn4401b. Moreover, we detected the presence of a class 1 integron containing a new allele, arr-8, followed by a 5'-truncated dhfrIIIc gene. in view of the recent results, we emphasize the high variability of the bacterial and genetic hosts of this resistance determinant.
Citation
Antimicrobial Agents and Chemotherapy. Washington: Amer Soc Microbiology, v. 57, n. 8, p. 4077-4078, 2013.
Sponsorship
Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)
Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)
FACEPE
PFA/UPE
URI
http://repositorio.unifesp.br/handle/11600/36563
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