Biological applications of peptides nanotubes: An overview

Biological applications of peptides nanotubes: An overview

Author Seabra, Amedea B. Autor UNIFESP Google Scholar
Duran, Nelson Google Scholar
Institution Universidade Federal de São Paulo (UNIFESP)
Universidade Federal do ABC (UFABC)
Universidade Estadual de Campinas (UNICAMP)
Abstract Recently, self-assemblies of peptide nanotubes (PNTs) have appeared as one of the most interesting nanostructures to be explored in the field of nanotechnology. These smart assemblies can have diverse applications, such as in the design of nanoreactors, sensors, electronics, and stimulus-responsive materials. Recent publications indicate that PNT synthesis and production are under extensive study. However, a more detailed safety and nanotoxicology evaluation of these materials is still necessary. This is of paramount importance since interesting and novel biomedical applications based on the use of PNTs, including the development of smart nanodevices and drug delivery systems, are under way. To this end, the aim of this mini-review is to discuss the recent biomedical applications of PNTs and, it hopes, to be a source of inspiration for researchers in different areas of expertise related to nanotechnology. (C) 2012 Elsevier Inc. All rights reserved.
Keywords Peptide nanotubes
Self-assembling peptides
Protein nanotubes
Drug release
Language English
Sponsor Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)
Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)
Grant number CNPq: 310209/2010-2
Date 2013-01-01
Published in Peptides. New York: Elsevier B.V., v. 39, p. 47-54, 2013.
ISSN 0196-9781 (Sherpa/Romeo, impact factor)
Publisher Elsevier B.V.
Extent 47-54
Access rights Closed access
Type Review
Web of Science ID WOS:000315839300008

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