Short and long term impact of adenotonsillectomy on the immune system

Show simple item record

dc.contributor.author Santos, Fabio Pires [UNIFESP]
dc.contributor.author Weber, Raimar
dc.contributor.author Fortes, Bibiana Callegaro
dc.contributor.author Nagata Pignatari, Shirley Shizue [UNIFESP]
dc.date.accessioned 2016-01-24T14:30:58Z
dc.date.available 2016-01-24T14:30:58Z
dc.date.issued 2013-01-01
dc.identifier http://dx.doi.org/10.5935/1808-8694.20130006
dc.identifier.citation Brazilian Journal of Otorhinolaryngology. São Paulo: Assoc Brasileira Otorrinolaringologia & Cirurgia Cervicofacial, v. 79, n. 1, p. 28-34, 2013.
dc.identifier.issn 1808-8694
dc.identifier.uri http://repositorio.unifesp.br/handle/11600/35760
dc.description.abstract Palatine and pharyngeal tonsils are immune reactive lymphoid organs that manifest specific antibodies and B/T-cell activity to respond to a variety of antigens. They perform humoral and cellular immune functions. the possible effects of adenotonsillectomy upon the immune system remain controversial.Objective: To study the short and long-term impacts of tonsillectomy upon the cellular and humoral immunity of children.Method: This longitudinal prospective study included 29 children referred to adenotonsillectomy for adenotonsillar hypertrophy. Serum IgA, IgM, and IgG and lymphocyte counts were analyzed at three points in time: before surgery, 1-2 month's after surgery (short term), and 12-14 months after surgery (long term).Results: TCD4+ cell counts were significantly increased shortly after surgery. IgA and IgG values were significantly reduced in the long run, but were within normal ranges for this age group.Conclusion: 'This study indicated that adenotonsillectomy does not pose negative short or long term impacts upon the cellular and humoral immunity of children submitted to the procedure. en
dc.format.extent 28-34
dc.language.iso eng
dc.publisher Assoc Brasileira Otorrinolaringologia & Cirurgia Cervicofacial
dc.relation.ispartof Brazilian Journal of Otorhinolaryngology
dc.rights Acesso aberto
dc.subject adenoidectomy en
dc.subject child en
dc.subject immune system en
dc.title Short and long term impact of adenotonsillectomy on the immune system en
dc.title.alternative Repercussão da adenotonsilectomia sobre o sistema imune a curto e longo prazo pt
dc.type Artigo
dc.contributor.institution Universidade Federal de São Paulo (UNIFESP)
dc.contributor.institution Prof Edmundo Vasconcelos Hosp
dc.contributor.institution Universidade de São Paulo (USP)
dc.contributor.institution Prof Edmund Vasconcelos Hosp
dc.contributor.institution Brazilian ENT HNS Assoc
dc.description.affiliation UNIFESP EPM, Otol & Ear Surg Serv, São Paulo, Brazil
dc.description.affiliation Prof Edmundo Vasconcelos Hosp, ENT Clin, Brazilian ENT HNS Assoc ENT, Moema, SP, Brazil
dc.description.affiliation FMUSP, São Paulo, Brazil
dc.description.affiliation Prof Edmund Vasconcelos Hosp, ENT Clin, Moema, SP, Brazil
dc.description.affiliation UNIFESP EPM, São Paulo, Brazil
dc.description.affiliation Brazilian ENT HNS Assoc, São Paulo, Brazil
dc.description.affiliation Prof Edmundo Vasconcelos Hosp, ENT Clin, UNIFESP EPM ENT, Dept ENT, Moema, SP, Brazil
dc.description.affiliation Prof Edmundo Vasconcelos Hosp, ENT Clin, Moema, SP, Brazil
dc.description.affiliationUnifesp UNIFESP EPM, Otol & Ear Surg Serv, São Paulo, Brazil
dc.description.affiliationUnifesp UNIFESP EPM, São Paulo, Brazil
dc.description.affiliationUnifesp Prof Edmundo Vasconcelos Hosp, ENT Clin, UNIFESP EPM ENT, Dept ENT, Moema, SP, Brazil
dc.identifier.file S1808-86942013000100006.pdf
dc.identifier.scielo S1808-86942013000100006
dc.identifier.doi 10.5935/1808-8694.20130006
dc.description.source Web of Science
dc.identifier.wos WOS:000315660800006



File

Name: S1808-86942013000100006.pdf
Size: 297.6Kb
Format: PDF
Description:
Open file

This item appears in the following Collection(s)

Show simple item record

Search


Browse

Statistics

My Account