• RI - Unifesp
    • Documentos
    • Tutoriais
    • Perguntas frequentes
    • Atendimento
    • Equipe
    • português (Brasil)
    • English
    • español
  • Sobre
    • RI Unifesp
    • Documentos
    • Tutoriais
    • Perguntas frequentes
    • Atendimento
    • Equipe
  • English 
    • português (Brasil)
    • English
    • español
    • português (Brasil)
    • English
    • español
  • Login
View Item 
  •   DSpace Home
  • Instituto de Saúde e Sociedade (ISS)
  • ISS - Outras produções
  • View Item
  •   DSpace Home
  • Instituto de Saúde e Sociedade (ISS)
  • ISS - Outras produções
  • View Item
JavaScript is disabled for your browser. Some features of this site may not work without it.

Effectiveness of probiotics in the prophylaxis of necrotizing enterocolitis in preterm neonates: a systematic review and meta-analysis

Thumbnail
View/Open
S0021-75572013000100004.pdf (427.1Kb)
Date
2013-01-01
Author
Bernardo, Wanderley Marques
Aires, Felipe Toyama
Carneiro, Renata Mota
Sá, Fernando Pereira de
Rullo, Vera Esteves Vagnozzi [UNIFESP]
Burns, Dennis Alexander
Type
Resenha
ISSN
0021-7557
Is part of
Jornal de Pediatria
DOI
10.1016/j.jped.2013.02.004
Metadata
Show full item record
Abstract
Objective: To elucidate the benefits of using probiotics in the prevention of necrotizing enterocolitis (NEC) and its complications in preterm newborns.Method: This was a systematic review of randomized controlled trials, which included studies retrieved from three databases (MEDLINE, Embase, and LILACS), using a combination of the terms (necrotizing enterocolitis) and (probiotics).Results: 11 randomized trials were included, totaling 2,887 patients, 1,431 in the probiotic group and 1,456 in the control group. There was a reduction in the incidence of NEC (NNT = 25), overall death (NNT = 34), and neonatal sepsis (NNT = 34) in the probiotic group compared to the control group. Patients that received probiotic supplementation had lower food reintroduction time (p < 0.001) and hospitalization time (p < 0.001) when compared to those not receiving probiotics. There was no difference in mortality caused by NEC.Conclusion: in premature newborns, the use of probiotics is effective as a prophylaxis for NEC and its complications. (C) 2013 Sociedade Brasileira de Pediatria. Published by Elsevier Editora Ltda. All rights reserved.
Citation
Jornal de Pediatria. Rio de Janeiro, Rj: Soc Brasil Pediatria, v. 89, n. 1, p. 18-24, 2013.
Keywords
Necrotizing enterocolitis
Probiotics
Premature
URI
http://repositorio.unifesp.br/handle/11600/35650
Collections
  • ISS - Outras produções [73]

DSpace software copyright © 2002-2016  DuraSpace
Contact Us
Theme by 
Atmire NV
 

 

Browse

All of DSpaceCommunities & CollectionsBy Issue DateAuthorsTitlesSubjectsBy Submit DateThis CollectionBy Issue DateAuthorsTitlesSubjectsBy Submit Date

My Account

Login

Statistics

View Usage Statistics

DSpace software copyright © 2002-2016  DuraSpace
Contact Us
Theme by 
Atmire NV