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dc.contributor.authorBorin, Andrei [UNIFESP]
dc.contributor.authorMello, Luiz Eugenio Araujo M. [UNIFESP]
dc.contributor.authorNeiva, Felipe Costa [UNIFESP]
dc.contributor.authorGurgel Testa, Jose Ricardo [UNIFESP]
dc.contributor.authorMendonca Cruz, Oswaldo Laercio [UNIFESP]
dc.date.accessioned2016-01-24T14:28:07Z
dc.date.available2016-01-24T14:28:07Z
dc.date.issued2012-12-01
dc.identifierhttp://dx.doi.org/10.1097/MAO.0b013e31826939e4
dc.identifier.citationOtology & Neurotology. Philadelphia: Lippincott Williams & Wilkins, v. 33, n. 9, p. 1625-1629, 2012.
dc.identifier.issn1531-7129
dc.identifier.urihttp://repositorio.unifesp.br/handle/11600/35588
dc.description.abstractBackground: the establishment of reliable methods for functional assessment in experimental models of peripheral nerve regeneration is crucial.Methods: We present a straightforward method for video analysis of the eye blink reflex in a model of facial nerve damage in a nonhuman primate (Callithrix sp.).Results: Our 6-level dynamic analysis demonstrated good reproducibility between independent observers, as measured by Cohen's kappa index. Our static analysis, which was based on 4 semi-automated metric parameters, showed low correlation during the early stage of facial movement recovery (the first and second weeks), but the correlation was excellent during the later stage of recovery (the third and fourth weeks).Conclusion: Altogether, our results establish a viable and readily accessible method with good reproducibility and correlation for the analysis of functional facial nerve recovery in an experimental model and based on video images of the eye blink reflex.en
dc.description.sponsorshipFundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)
dc.format.extent1625-1629
dc.language.isoeng
dc.publisherLippincott Williams & Wilkins
dc.relation.ispartofOtology & Neurotology
dc.rightsAcesso restrito
dc.subjectFacial nerveen
dc.subjectFacial paralysisen
dc.subjectNerve regenerationen
dc.subjectPrimatesen
dc.titleExperimental Video Analysis of Eye Blink Reflex in a Primate Modelen
dc.typeArtigo
dc.contributor.institutionUniversidade Federal de São Paulo (UNIFESP)
dc.description.affiliationUniversidade Federal de São Paulo, Dept Otorhinolaryngol Head & Neck Surg, São Paulo, Brazil
dc.description.affiliationUniversidade Federal de São Paulo, Dept Physiol, São Paulo, Brazil
dc.description.affiliationUnifespUniversidade Federal de São Paulo, Dept Otorhinolaryngol Head & Neck Surg, São Paulo, Brazil
dc.description.affiliationUnifespUniversidade Federal de São Paulo, Dept Physiol, São Paulo, Brazil
dc.description.sponsorshipIDFAPESP: 2009/52805-7
dc.identifier.doi10.1097/MAO.0b013e31826939e4
dc.description.sourceWeb of Science
dc.identifier.wosWOS:000311214500034


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