Airflow Obstruction in Never Smokers in Five Latin American Cities: the PLATINO Study
Nenhuma Miniatura disponível
Data
2012-02-01
Autores
Perez-Padilla, Rogelio
Fernandez, Rosario
Lopez Varela, Maria Victorina
Montes de Oca, Maria
Muino, Adriana
Talamo, Carlos
Brito Jardim, Jose Roberto [UNIFESP]
Valdivia, Gonzalo
Baptista Menezes, Ana Maria
Orientadores
Tipo
Artigo
Título da Revista
ISSN da Revista
Título de Volume
Resumo
Background. Although chronic obstructive pulmonary disease (COPD) is mostly related to tobacco smoking, a variable proportion of COPD occurs in never smokers. We investigated differences between COPD in never smokers compared with smokers and subjects without COPD.Methods. PLATINO is a cross-sectional population-based study of five Latin American cities. COPD was defined as postbronchodilator FEV1/FVC <0.70 and FEV1 <80% of predicted values.Results. Among 5,315 subjects studied, 2278 were never smokers and 3036 were ever smokers. COPD was observed in 3.5% of never smokers and in 7.5% of ever smokers. Never smokers with COPD were most likely older and reported a medical diagnosis of asthma or previous tuberculosis. Underdiagnosis was as common in obstructed patients who never smoked as in ever smokers.Conclusions. Never smokers comprised 26% of all individuals with airflow obstruction. Obstruction was associated with female gender, older age and a diagnosis of asthma or tuberculosis. (C) 2012 IMSS. Published by Elsevier Inc.
Descrição
Citação
Archives of Medical Research. New York: Elsevier B.V., v. 43, n. 2, p. 159-165, 2012.