Airflow Obstruction in Never Smokers in Five Latin American Cities: the PLATINO Study

Show simple item record Perez-Padilla, Rogelio Fernandez, Rosario Lopez Varela, Maria Victorina Montes de Oca, Maria Muino, Adriana Talamo, Carlos Brito Jardim, Jose Roberto [UNIFESP] Valdivia, Gonzalo Baptista Menezes, Ana Maria 2016-01-24T14:17:52Z 2016-01-24T14:17:52Z 2012-02-01
dc.identifier.citation Archives of Medical Research. New York: Elsevier B.V., v. 43, n. 2, p. 159-165, 2012.
dc.identifier.issn 0188-4409
dc.description.abstract Background. Although chronic obstructive pulmonary disease (COPD) is mostly related to tobacco smoking, a variable proportion of COPD occurs in never smokers. We investigated differences between COPD in never smokers compared with smokers and subjects without COPD.Methods. PLATINO is a cross-sectional population-based study of five Latin American cities. COPD was defined as postbronchodilator FEV1/FVC <0.70 and FEV1 <80% of predicted values.Results. Among 5,315 subjects studied, 2278 were never smokers and 3036 were ever smokers. COPD was observed in 3.5% of never smokers and in 7.5% of ever smokers. Never smokers with COPD were most likely older and reported a medical diagnosis of asthma or previous tuberculosis. Underdiagnosis was as common in obstructed patients who never smoked as in ever smokers.Conclusions. Never smokers comprised 26% of all individuals with airflow obstruction. Obstruction was associated with female gender, older age and a diagnosis of asthma or tuberculosis. (C) 2012 IMSS. Published by Elsevier Inc. en
dc.description.sponsorship Asociacion Latinoamericana de Torax (ALAT)
dc.format.extent 159-165
dc.language.iso eng
dc.publisher Elsevier B.V.
dc.relation.ispartof Archives of Medical Research
dc.rights Acesso restrito
dc.subject Chronic pulmonary disease en
dc.subject Epidemiology en
dc.subject Never smokers en
dc.subject Health status en
dc.subject Tobacco smoking en
dc.title Airflow Obstruction in Never Smokers in Five Latin American Cities: the PLATINO Study en
dc.type Artigo
dc.contributor.institution Inst Nacl Enfermedades Resp
dc.contributor.institution Univ Republica
dc.contributor.institution Cent Univ Venezuela
dc.contributor.institution Universidade Federal de São Paulo (UNIFESP)
dc.contributor.institution Pontificia Univ Catolica Chile
dc.description.affiliation Inst Nacl Enfermedades Resp, Mexico City 14080, DF, Mexico
dc.description.affiliation Univ Republica, Fac Med, Montevideo, Uruguay
dc.description.affiliation Cent Univ Venezuela, Fac Med, Caracas, Venezuela
dc.description.affiliation Universidade Federal de São Paulo, São Paulo, Brazil
dc.description.affiliation Pontificia Univ Catolica Chile, Santiago, Chile
dc.description.affiliationUnifesp Universidade Federal de São Paulo, São Paulo, Brazil
dc.identifier.doi 10.1016/j.arcmed.2012.03.007
dc.description.source Web of Science
dc.identifier.wos WOS:000304507800010


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