The Effects of Physical Exercise on the Serum Iron Profile in Spontaneously Hypertensive Rats
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2012-02-01
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Frank, Miriam K. [UNIFESP]
Esteves, Andrea Maculano [UNIFESP]
Lopes, Cleide [UNIFESP]
Cavagnolli, Daniel A. [UNIFESP]
Tufik, Sergio [UNIFESP]
Mello, Marco Tulio de [UNIFESP]
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The purpose of this study was to evaluate the profile of serum iron in spontaneously hypertensive rats after an aerobic physical exercise. To accomplish this, 12 normotensive Wistar rats and 12 spontaneously hypertensive rats were distributed into physical exercise and no physical exercise groups. the animals in the physical exercise group underwent to an aerobic exercise for a total of 4 weeks. Blood was collected for the analysis of iron. Our results indicate that rats of the physical exercise group had significantly lower serum iron levels after the aerobic exercise protocol compared to the spontaneously hypertensive rats no physical exercise group (F ((3,16)) = 4.4915, p < 0.01). No significant difference was found between no physical exercise groups. the results indicated that the difference in iron may be due to an increased demand for iron, prompted by chronic physical exercise. in addition, erythrocytosis has been associated with increased blood pressure in spontaneously hypertensive rats, suggesting that iron reduction may be related to decreased blood pressure in these animals.
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Biological Trace Element Research. Totowa: Humana Press Inc, v. 145, n. 2, p. 222-224, 2012.