Comparative Study of the Standard Fluorescent Antibody to Membrane Antigen (FAMA) Assay and a Flow Cytometry-Adapted FAMA Assay To Assess Immunity to Varicella-Zoster Virus

Comparative Study of the Standard Fluorescent Antibody to Membrane Antigen (FAMA) Assay and a Flow Cytometry-Adapted FAMA Assay To Assess Immunity to Varicella-Zoster Virus

Author Lafer, Manuel Mindlin Autor UNIFESP Google Scholar
Weckx, L. Y. Autor UNIFESP Google Scholar
Moraes-Pinto, M. I. de Autor UNIFESP Google Scholar
Garretson, A. Google Scholar
Steinberg, S. P. Google Scholar
Gershon, A. A. Google Scholar
LaRussa, P. S. Google Scholar
Institution Universidade Federal de São Paulo (UNIFESP)
Columbia Univ
Abstract A flow cytometry-adapted fluorescent antibody to membrane antigen (FAMA) assay to detect IgG antibodies against varicella-zoster virus (VZV) was developed and tested in 62 serum samples, showing 90.32% accuracy obtained from a receiver operating characteristic (ROC) curve with a 0.9125 (95% confidence interval [CI], 0.829 to 1.00) area below the curve compared to the result with standard FAMA.
Language English
Sponsor Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)
Grant number CAPES: 0108-08-1
Date 2011-07-01
Published in Clinical and Vaccine Immunology. Washington: Amer Soc Microbiology, v. 18, n. 7, p. 1194-1197, 2011.
ISSN 1556-6811 (Sherpa/Romeo, impact factor)
Publisher Amer Soc Microbiology
Extent 1194-1197
Origin http://dx.doi.org/10.1128/CVI.05130-11
Access rights Open access Open Access
Type Article
Web of Science ID WOS:000292378200023
URI http://repositorio.unifesp.br/handle/11600/33828

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