Cesarean delivery is associated with an increased risk of obesity in adulthood in a Brazilian birth cohort study

Nenhuma Miniatura disponível
Goldani, Helena A. S.
Bettiol, Heloisa
Barbieri, Marco A.
Silva, Antonio A. M.
Agranonik, Marilyn
Morais, Mauro Batista de [UNIFESP]
Goldani, Marcelo Z.
Título da Revista
ISSN da Revista
Título de Volume
Background: Obesity is epidemic worldwide, and increases in cesarean delivery rates have occurred in parallel.Objective: This study aimed to determine whether cesarean delivery is a risk factor for obesity in adulthood in a birth cohort of Brazilian subjects.Design: We initiated a birth cohort study in Ribeirao Preto, southeastern Brazil, in 1978. A randomly selected sample of 2057 subjects from the original cohort was reassessed in 2002-2004. Type of delivery, birth weight, maternal smoking, and schooling were obtained after birth. the following data from subjects were collected at 23-25 y of age: body mass index (BMI; in kg/m(2)), physical activity, smoking, and income. Obesity was defined as a BMI >= 30. A Poisson multivariable model was performed to determine the association between cesarean delivery and BMI.Results: the obesity rate in adults born by cesarean delivery was 15.2% and in those born by vaginal delivery was 10.4% (P = 0.002). Adults born by cesarean delivery had an increased risk (prevalence ratio: 1.58; 95% CI: 1.23, 2.02) of obesity at adulthood after adjustments.Conclusion: We hypothesize that increasing rates of cesarean delivery may play a role in the obesity epidemic worldwide. Am J Clin Nutr 2011;93:1344-7.
American Journal of Clinical Nutrition. Bethesda: Amer Soc Clinical Nutrition, v. 93, n. 6, p. 1344-1347, 2011.