Neurobehavior of Late Preterm Infants of Adolescent Mothers

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dc.contributor.author Barros, Marina C. M. [UNIFESP]
dc.contributor.author Mitsuhiro, Sandro [UNIFESP]
dc.contributor.author Chalem, Elisa [UNIFESP]
dc.contributor.author Laranjeira, Ronaldo R. [UNIFESP]
dc.contributor.author Guinsburg, Ruth [UNIFESP]
dc.date.accessioned 2016-01-24T14:06:01Z
dc.date.available 2016-01-24T14:06:01Z
dc.date.issued 2011-01-01
dc.identifier http://dx.doi.org/10.1159/000313590
dc.identifier.citation Neonatology. Basel: Karger, v. 99, n. 2, p. 133-139, 2011.
dc.identifier.issn 1661-7800
dc.identifier.uri http://repositorio.unifesp.br/handle/11600/33324
dc.description.abstract Background: Late preterm infants have higher morbidity in the neonatal period and difficulties at school age. There are few data about neonatal neurobehavior performance that may interfere in their development. Objectives: To compare the neurobehavior of healthy late preterm and full-term neonates born to adolescent mothers. Methods: This prospective cross-sectional study included infants with a gestational age of 40(0/7)-40(6/7) weeks (full term) and 34(0/7)-36(6/7) weeks (late preterm) aged 24-72 h without exposure to alcohol, tobacco, drugs or infections and free of clinical problems during the first 3 days of life. Infants were assessed with the Neonatal Intensive Care Unit Network Neurobehavioral Scale (NNNS). Outcomes were analyzed by ANOVA. Results: From July 2001 to November 2002, 3,685 infants were born, 928 of adolescent mothers. After exclusion, 36 late preterm and 96 term infants were enrolled. Adjusted for anesthesia type, delivery mode, gender, age at NNNS examination, time between last feeding and examination, and examination duration, late preterm, compared to term neonates, presented lower scores for attention (p = 0.041), arousal (p = 0.011), regulation (p < 0.001), quality of movements (p < 0.001) and higher scores for non-optimal reflexes (p < 0.001) and hypotonicity (p = 0.029). Conclusion: Late preterm infants of adolescent mothers have a more immature neurobehavioral performance at 24-72 h of life in multiple areas compared to term neonates suggesting a need for careful follow-up. Copyright (C) 2010 S. Karger AG, Basel en
dc.description.sponsorship Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)
dc.format.extent 133-139
dc.language.iso eng
dc.publisher Karger
dc.relation.ispartof Neonatology
dc.rights Acesso restrito
dc.subject Late preterm infant en
dc.subject Neurologic examination en
dc.subject Adolescent mothers en
dc.title Neurobehavior of Late Preterm Infants of Adolescent Mothers en
dc.type Artigo
dc.rights.license http://www.karger.com/Services/RightsPermissions
dc.contributor.institution Universidade Federal de São Paulo (UNIFESP)
dc.description.affiliation Universidade Federal de São Paulo, Div Neonatal Med, Dept Pediat, BR-01410020 São Paulo, Brazil
dc.description.affiliation Universidade Federal de São Paulo, Res Unit Alcohol & Drugs, BR-01410020 São Paulo, Brazil
dc.description.affiliation Universidade Federal de São Paulo, Dept Psychiat, BR-01410020 São Paulo, Brazil
dc.description.affiliationUnifesp Universidade Federal de São Paulo, Div Neonatal Med, Dept Pediat, BR-01410020 São Paulo, Brazil
dc.description.affiliationUnifesp Universidade Federal de São Paulo, Res Unit Alcohol & Drugs, BR-01410020 São Paulo, Brazil
dc.description.affiliationUnifesp Universidade Federal de São Paulo, Dept Psychiat, BR-01410020 São Paulo, Brazil
dc.description.sponsorshipID FAPESP: 2000/10293-5
dc.identifier.doi 10.1159/000313590
dc.description.source Web of Science
dc.identifier.wos WOS:000284158900009



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