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dc.contributor.authorCarvalho, Tatiana Dias de [UNIFESP]
dc.contributor.authorPastre, Carlos Marcelo
dc.contributor.authorGodoy, Moacir Fernandes de
dc.contributor.authorFereira, Celso [UNIFESP]
dc.contributor.authorPitta, Fabio O.
dc.contributor.authorAbreu, Luiz Carlos de
dc.contributor.authorRamos, Ercy Mara Cipulo [UNIFESP]
dc.contributor.authorValenti, Vitor Engrácia [UNIFESP]
dc.contributor.authorVanderlei, Luiz Carlos Marques
dc.identifier.citationInternational Journal of Chronic Obstructive Pulmonary Disease. Albany: Dove Medical Press Ltd, v. 6, p. 23-28, 2011.
dc.description.abstractBackground: It was reported that autonomic nervous system function is altered in subjects with chronic obstructive pulmonary disease (COPD). We evaluated short-and long-term fractal exponents of heart rate variability (HRV) in COPD subjects.Patients and methods: We analyzed data from 30 volunteers, who were divided into two groups according to spirometric values: COPD (n = 15) and control (n = 15). for analysis of HRV indices, HRV was recorded beat by beat with the volunteers in the supine position for 30 minutes. We analyzed the linear indices in the time (SDNN [standard deviation of normal to normal] and RMSSD [root-mean square of differences]) and frequency domains (low frequency [LF], high frequency [HF], and LF/HF), and the short-and long-term fractal exponents were obtained by detrended fluctuation analysis. We considered P < 0.05 to be a significant difference.Results: COPD patients presented reduced levels of all linear exponents and decreased short-term fractal exponent (alpha-1: 0.899 +/- 0.18 versus 1.025 +/- 0.09, P = 0.026). There was no significant difference between COPD and control groups in alpha-2 and alpha-1/alpha-2 ratio.Conclusion: COPD subjects present reduced short-term fractal correlation properties of HRV, which indicates that this index can be used for risk stratification, assessment of systemic disease manifestations, and therapeutic procedures to monitor those patients.en
dc.description.sponsorshipFundação para o Desenvolvimento da UNESP (FUNDUNESP)
dc.publisherDove Medical Press Ltd
dc.relation.ispartofInternational Journal of Chronic Obstructive Pulmonary Disease
dc.rightsAcesso aberto
dc.subjectpulmonary diseaseen
dc.subjectchronic obstructiveen
dc.subjectheart rateen
dc.subjectnervous systemen
dc.titleFractal correlation property of heart rate variability in chronic obstructive pulmonary diseaseen
dc.contributor.institutionUniv Estadual Paulista
dc.contributor.institutionUniversidade Federal de São Paulo (UNIFESP)
dc.contributor.institutionFac Med Sao Jose do Rio Preto
dc.contributor.institutionUniversidade Estadual de Londrina (UEL)
dc.contributor.institutionFac Med ABC
dc.description.affiliationUniv Estadual Paulista, Fac Ciencias & Tecnol, Dept Fisioterapia, São Paulo, Brazil
dc.description.affiliationUniversidade Federal de São Paulo, Disciplina Cardiol, Dept Med, São Paulo, Brazil
dc.description.affiliationFac Med Sao Jose do Rio Preto, Dept Cardiol & Cirurgia Cardiovasc, São Paulo, Brazil
dc.description.affiliationUniv Estadual Londrina, Lab Pesquisa Fisioterapia Pulm, Dept Fisioterapia, Londrina, Brazil
dc.description.affiliationFac Med ABC, Dept Morfol & Fisiol, Santo Andre, Brazil
dc.description.affiliationUnifespUniversidade Federal de São Paulo, Disciplina Cardiol, Dept Med, São Paulo, Brazil
dc.description.sponsorshipIDFUNDUNESP: 00704/08 - DFP
dc.description.sourceWeb of Science

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