Evaluation of 25-Hydroxyvitamin D Serum Levels in Patients With Fibromyalgia
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Data
2010-12-01
Autores
Pena, Caris de Rezende
Grillo, Luciane Peter [UNIFESP]
das Chagas Medeiros, Marta Maria
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Background: Fibromyalgia (FM) is a condition characterized by chronic widespread musculoskeletal pain often associated with sleep disorders and mood and whose pathophysiology is still not clearly defined. in recent years, some studies have hinted at a possible association between different types of pain, including the pain present in FM, with vitamin D deficiency.Objective and Methods: the present work consisted of a cross-sectional study aimed at evaluating 25-hydroxyvitamin D (25(OH) D) serum levels in 87 patients with FM, as compared with a control group composed of 92 age- and sex-matched subjects with no chronic musculoskeletal pain. Clinical and laboratory variables that could affect the status of vitamin D were also considered.Results: There was no statistically significant difference between groups either with respect to mean serum concentration of 25(OH) D or as to the classification of levels as deficient, insufficient, or sufficient. There was no correlation of 25(OH) D levels with pain intensity.Conclusion: This study showed that light to moderate deficient and insufficient 25(OH) D levels are not found more commonly in patients with FM.
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Jcr-Journal of Clinical Rheumatology. Philadelphia: Lippincott Williams & Wilkins, v. 16, n. 8, p. 365-369, 2010.