Now showing items 1-10 of 322

    • Prenatal and lactation nicotine exposure affects Sertoli cell and gonadotropin levels in rats 

      Paccola, C. C. [UNIFESP]; Miraglia, S. M. [UNIFESP] (Bioscientifica Ltd, 2016)
      Nicotine is largely consumed in the world as a component of cigarettes. It can cross the placenta and reach the milk of smoking mothers. This drug induces apoptosis, affects sex hormone secretion, and leads to male ...
    • Novel frameshift variant in gene SALL4 causing Okihiro syndrome 

      Alves, Leandro Ucela; Alvarez Perez, Ana Beatriz [UNIFESP]; Alonso, Luis Garcia [UNIFESP]; Otto, Paulo Alberto; Mingroni-Netto, Regina Celia (Elsevier Science Bv, 2016)
      Okihiro syndrome, Duane-radial ray syndrome or acro-reno-ocular syndrome (OMIM #607323) are alternative denominations describing an extremely variable condition, characterized by several radial defects of the upper limbs ...
    • The essential role of annexin A1 mimetic peptide in the skin allograft survival 

      Teixeira, Rodrigo Antonio Parra [UNIFESP]; Mimura, Kallyne Kioko Oliveira [UNIFESP]; Araujo, Leandro Pires [UNIFESP]; Greco, Karin Vicente; Oliani, Sonia Maria [UNIFESP] (Wiley-Blackwell, 2016)
      Immunosuppressive drugs have a critical role in inhibiting tissue damage and allograft rejection. Studies have demonstrated the anti-inflammatory effects of the annexin A1 (AnxA1) in the regulation of transmigration and ...
    • Prenatal and lactation nicotine exposure affects Sertoli cell and gonadotropin levels in rats 

      Paccola, C. C. [UNIFESP]; Miraglia, S. M. [UNIFESP] (Bioscientifica Ltd, 2016)
      Nicotine is largely consumed in the world as a component of cigarettes. It can cross the placenta and reach the milk of smoking mothers. This drug induces apoptosis, affects sex hormone secretion, and leads to male ...
    • Novel frameshift variant in gene SALL4 causing Okihiro syndrome 

      Alves, Leandro Ucela; Alvarez Perez, Ana Beatriz [UNIFESP]; Alonso, Luis Garcia [UNIFESP]; Otto, Paulo Alberto; Mingroni-Netto, Regina Celia (Elsevier Science Bv, 2016)
      Okihiro syndrome, Duane-radial ray syndrome or acro-reno-ocular syndrome (OMIM #607323) are alternative denominations describing an extremely variable condition, characterized by several radial defects of the upper limbs ...
    • The essential role of annexin A1 mimetic peptide in the skin allograft survival 

      Teixeira, Rodrigo Antonio Parra [UNIFESP]; Mimura, Kallyne Kioko Oliveira [UNIFESP]; Araujo, Leandro Pires [UNIFESP]; Greco, Karin Vicente; Oliani, Sonia Maria [UNIFESP] (Wiley-Blackwell, 2016)
      Immunosuppressive drugs have a critical role in inhibiting tissue damage and allograft rejection. Studies have demonstrated the anti-inflammatory effects of the annexin A1 (AnxA1) in the regulation of transmigration and ...
    • The antineoplastic busulphan impairs peritubular and Leydig cells, and vitamin B-12 stimulates spermatogonia proliferation and prevents busulphan-induced germ cell death 

      Sasso-Cerri, Estela; Oliveira, Barbara; de Santi, Fabiane [UNIFESP]; Beltrame, Flavia L. [UNIFESP]; Caneguim, Breno H. [UNIFESP]; Cerri, Paulo S. (Elsevier France-Editions Scientifiques Medicales Elsevier, 2017)
      Busulphan (Bu), an alkylating agent used for bone marrow and spermatogonial stem cell transplantation (SSCT), impairs Sertoli (SC) cells, which are necessary for the spermatogonial stem cell (SSC) homing during transplantation. ...
    • Determining the frequency of morphological characteristics in a sample of Brazilian children 

      Perrone, Eduardo [UNIFESP]; Zanolla, Thais Arbocese [UNIFESP]; Fock, Rodrigo Ambrosio [UNIFESP]; Alvarez Perez, Ana Beatriz [UNIFESP]; Brunoni, Decio (Soc Brasil Pediatria, 2017)
      Objective: To establish the frequency of 82 morphological features in a sample of Brazilian children (between 3 and 13 years old), to understand the influence of age, gender, and ethnicity. Methods: This was a cross-sectional ...
    • AN OBSERVATIONAL STUDY OF CHILDREN OF MOTHERS WITH GENETIC GENERALIZED EPILEPSY EXPOSED TO ANTIEPILEPTIC MEDICATIONS DURING PREGNANCY 

      Zetehaku, A. C. [UNIFESP]; Torres Corso, J. [UNIFESP]; Botelho Gaca, L. [UNIFESP]; Rodrigues De Marchi, L. [UNIFESP]; Visona Figueiredo, N. S. [UNIFESP]; Almeida Barbosa, R. H. [UNIFESP]; Fock, R. [UNIFESP]; Perrone, E. [UNIFESP]; Alvarez Perez, A. B. [UNIFESP]; Guaranha, M. S. [UNIFESP]; Yacubian, E. M. [UNIFESP] (Wiley, 2017)
    • Patients with a Kabuki syndrome phenotype demonstrate DNA methylation abnormalities 

      Sobreira, Nara; Brucato, Martha; Zhang, Li; Ladd-Acosta, Christine; Ongaco, Chrissie; Romm, Jane; Doheny, Kimberly F.; Mingroni-Netto, Regina C.; Bertola, Debora; Kim, Chong A.; Perez, Ana B. A. [UNIFESP]; Melaragno, Maria I. [UNIFESP]; Valle, David; Meloni, Vera A.; Bjornsson, Hans T. (Nature Publishing Group, 2017)
      Kabuki syndrome is a monogenic disorder caused by loss of function variants in either of two genes encoding histone-modifying enzymes. We performed targeted sequencing in a cohort of 27 probands with a clinical diagnosis ...