Application of computed tomography images in the evaluation of magnetic nanoparticles biodistribution
Data
2010-08-01
Autores
Levenhagen, Ronaldo Savarino 
Tipo
Artigo
Título da Revista
ISSN da Revista
Título de Volume
Resumo
In this work we evaluate the effectiveness of computed tomography images as a tool to determine magnetic nanoparticle biodistribution over biological tissues. for this purpose, tomography images for magnetic nanoparticles, composed of Fe(3)O(4), coated with 2,3-dimercaptosuccinic acid (DMSA), were generated at several material concentrations. the comparison of CT numbers, calculated from these images generated at clinical conditions, with typical CT numbers for biological tissues, shows that the detection of nanoparticle in most tissues is only possible for high material concentrations. (C) 2010 Elsevier B.V. All rights reserved.
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Citação
Journal of Magnetism and Magnetic Materials. Amsterdam: Elsevier B.V., v. 322, n. 16, p. 2405-2407, 2010.