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dc.contributor.authorLeao, Sylvia Cardoso [UNIFESP]
dc.contributor.authorViana-Niero, Cristina
dc.contributor.authorMatsumoto, Cristianne Kayoko
dc.contributor.authorBatista Lima, Karla Valeria
dc.contributor.authorLopes, Maria Luiza
dc.contributor.authorPalaci, Moises
dc.contributor.authorHadad, David Jamil
dc.contributor.authorVinhas, Solange
dc.contributor.authorDuarte, Rafael Silva
dc.contributor.authorSilva Lourenco, Maria Cristina
dc.contributor.authorKipnis, Andre
dc.contributor.authordas Neves, Zilah Candida
dc.contributor.authorAlcantara Gabardo, Betina Mendez
dc.contributor.authorRibeiro, Marta Osorio
dc.contributor.authorBaethgen, Ludmila
dc.contributor.authorAssis, Denise Brandao de
dc.contributor.authorMadalosso, Geraldine
dc.contributor.authorChimara, Erica
dc.contributor.authorDalcolmo, Margareth Pretti
dc.identifier.citationFuture Microbiology. London: Future Medicine Ltd, v. 5, n. 6, p. 971-980, 2010.
dc.description.abstractAim: Our aim is to investigate if the clusters of postsurgical mycobacterial infections, reported between 2004 and 2008 in seven geographically distant states in Brazil, were caused by a single mycobacterial strain. Materials & methods: Available information from 929 surgical patients was obtained from local health authorities. A total of 152 isolates from surgical patients were identified by PCR restriction enzyme analysis of the hsp65 gene (PRA-hsp65) and sequencing of the rpoB gene. Isolates were typed by pulsed-field gel electrophoresis (PFGE) using two restriction enzymes. Dral and Asel. A total of 15 isolates not related to surgical cases were analyzed for comparison. Results: All isolates were identified as Mycobacterium abscessus ssp. massiliense. Isolates from surgical patients and one sputum isolate grouped in a single PFGE cluster, composed of two closely related patterns, with one band difference. A total of 14 other isolates unrelated to surgical cases showed distinctive PFGE patterns. Conclusion: A particular strain of M. abscessus ssp. massiliense was associated with a prolonged epidemic of postsurgical infections in seven Brazilian states, suggesting that this strain may be distributed in Brazilian territory and better adapted to cause surgical-site infections.en
dc.description.sponsorshipFundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)
dc.description.sponsorshipConselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)
dc.publisherFuture Medicine Ltd
dc.relation.ispartofFuture Microbiology
dc.rightsAcesso restrito
dc.subjectmolecular identificationen
dc.subjectmolecular typingen
dc.subjectsurgical infectionen
dc.titleEpidemic of surgical-site infections by a single clone of rapidly growing mycobacteria in Brazilen
dc.contributor.institutionUniversidade Federal de São Paulo (UNIFESP)
dc.contributor.institutionUniv Fed Espirito Santo
dc.contributor.institutionInst Evandro Chagas
dc.contributor.institutionUniversidade Federal do Rio de Janeiro (UFRJ)
dc.contributor.institutionFundacao Oswaldo Cruz
dc.contributor.institutionUniversidade Federal de Goiás (UFG)
dc.contributor.institutionSecretaria Municipal Saude Goiania
dc.contributor.institutionSecretaria Estadual Saude Parana
dc.contributor.institutionLab Cent Saude Publ
dc.contributor.institutionCtr Vigilancia Epidemiol Prof Alexandre Vranjac
dc.contributor.institutionInst Adolfo Lutz Registro
dc.contributor.institutionCtr Referencia Prof Helio Fraga
dc.description.affiliationUniversidade Federal de São Paulo, Dept Microbiol Immunol & Parasitol, BR-04023062 São Paulo, Brazil
dc.description.affiliationUniv Fed Espirito Santo, Nucleo Doencas Infecciosas, Vitoria, ES, Brazil
dc.description.affiliationInst Evandro Chagas, Belem, Para, Brazil
dc.description.affiliationUniv Fed Rio de Janeiro, Inst Microbiol, BR-21941 Rio de Janeiro, Brazil
dc.description.affiliationFundacao Oswaldo Cruz, Inst Pesquisa Evandro Chagas, Rio de Janeiro, Brazil
dc.description.affiliationUniv Fed Goias, Dept Microbiol Imunol Parasitol & Patol, Goiania, Go, Brazil
dc.description.affiliationSecretaria Municipal Saude Goiania, Goiania, Go, Brazil
dc.description.affiliationSecretaria Estadual Saude Parana, Curitiba, Parana, Brazil
dc.description.affiliationLab Cent Saude Publ, Porto Alegre, RS, Brazil
dc.description.affiliationCtr Vigilancia Epidemiol Prof Alexandre Vranjac, São Paulo, Brazil
dc.description.affiliationInst Adolfo Lutz Registro, Setor Micobacterias, São Paulo, Brazil
dc.description.affiliationCtr Referencia Prof Helio Fraga, Rio de Janeiro, Brazil
dc.description.affiliationUnifespUniversidade Federal de São Paulo, Dept Microbiol Immunol & Parasitol, BR-04023062 São Paulo, Brazil
dc.description.sponsorshipIDFAPESP: 06/1533-9
dc.description.sponsorshipIDCNPq: 470594/2006-3
dc.description.sponsorshipIDCNPq: 475238/2008-7
dc.description.sourceWeb of Science

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