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dc.contributor.authorEickelmann, Mareike
dc.contributor.authorSteinhoff, Martin
dc.contributor.authorMetze, Dieter
dc.contributor.authorTomimori-Yamashita, Jane [UNIFESP]
dc.contributor.authorSunderkoetter, Cord
dc.identifier.citationJournal Der Deutschen Dermatologischen Gesellschaft. Malden: Wiley-Blackwell, v. 8, n. 6, p. 450-453, 2010.
dc.description.abstractP>Leprosy is usually well-controlled by multidrug therapy (MDT). However, in case of noncompliance or leprosy reactions, it may present a therapeutically challenge. A 33-year-old Brazilian woman with lepromatous leprosy was treated with MDT for one year, but then discontinued therapy because she wanted to have children. Eight weeks after stopping her medications, she developed a severe and recalcitrant erythema (nodosum) leprosum (ENL) which presented histologically with thrombosed small veins and neutrophilic inflammation in fat septa, but without arteritis. During her pregnancy and ensuing lactation period, glucocorticoids were the only suitable drug. With the use of the shortened WHO/MDT regimen (one year vs. two years of treatment), ENL will probably be seen more often after the end of leprosy therapy. It needs to be rapidly recognized and treated to avoid damage to eyes or kidneys.en
dc.relation.ispartofJournal Der Deutschen Dermatologischen Gesellschaft
dc.rightsAcesso restrito
dc.subjectmycobacterium lepraeen
dc.subjectErythema nodosumen
dc.subjectliprosy reactionen
dc.subjectdrug therapyen
dc.titleErythema leprosum - after treatment of Lepromatous Leprosyen
dc.contributor.institutionUniv Klinikum Munster
dc.contributor.institutionUniversidade Federal de São Paulo (UNIFESP)
dc.description.affiliationUniv Klinikum Munster, Klin & Poliklin Hautkrankheiten, Dermatol Clin, D-48149 Munster, Germany
dc.description.affiliationUniversidade Federal de São Paulo, Dept Dermatol, São Paulo, Brazil
dc.description.affiliationUnifespUniversidade Federal de São Paulo, Dept Dermatol, São Paulo, Brazil
dc.description.sourceWeb of Science

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