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dc.contributor.authorStrabelli, T. M. V.
dc.contributor.authorSiciliano, Rinaldo Focaccia
dc.contributor.authorCastelli, Jussara Bianchi
dc.contributor.authorDemarchi, L. M. M. F.
dc.contributor.authorLeao, Sylvia Cardoso [UNIFESP]
dc.contributor.authorViana-Niero, Cristina [UNIFESP]
dc.contributor.authorMiyashiro, Kozue
dc.contributor.authorSampaio, Roney Orismar
dc.contributor.authorGrinberg, Max
dc.contributor.authorUip, David Everson
dc.identifier.citationJournal of Infection. London: W B Saunders Co Ltd, v. 60, n. 6, p. 467-473, 2010.
dc.description.abstractObjectives: A rapid-growing mycobacteria biological prosthetic valve (BPV) endocarditis related to prosthetic manufacturing process is described in Brazil.Methods: From 1999 to 2008, thirty-nine patients underwent BPV replacement due to culture-negative suspected endocarditis. All these cases had histological sections stained by Ziehl-Neelsen method. Clinical and microbiological data were reviewed in all acid-fast bacilli (AFB) positive cases. the 16S-23S internal transcribed sequence (ITS) was amplified using DNA extracted from paraffin-embedded samples, digested with restrictions enzymes and/or sequenced.Results: Eighteen AFB positive BPV (18/39)(46%) were implanted in 13 patients and were from the same manufacturer. Four of them were implanted in other hospitals. Thirteen BPV were histologically proven endocarditis and five showed a colonization pattern. the examination of six non-implanted sterile BPV from this manufacturer resulted in 5 AFB positive. Mycobacterium chelonae was the AFB identified by ITS restriction analysis and sequencing.Conclusions: Rapid-growing mycobacteria infections must be suspected and Ziehl-Neelsen stain always performed on histology of either early or late BPV endocarditis, particularly when blood cultures are negative. (C) 2010 the British Infection Society. Published by Elsevier B.V. All rights reserved.en
dc.publisherW B Saunders Co Ltd
dc.relation.ispartofJournal of Infection
dc.rightsAcesso restrito
dc.subjectMycobacterium chelonaeen
dc.subjectCardiac valveen
dc.titleMycobacterium chelonae valve endocarditis resulting from contaminated biological prosthesesen
dc.contributor.institutionUniversidade de São Paulo (USP)
dc.contributor.institutionUniversidade Federal de São Paulo (UNIFESP)
dc.contributor.institutionInst Fleury
dc.description.affiliationUniv São Paulo, Heart Inst InCor, Hosp Clin, Fac Med, BR-05508 São Paulo, Brazil
dc.description.affiliationUniversidade Federal de São Paulo, Dept Microbiol Immunol & Parasitol, São Paulo, Brazil
dc.description.affiliationInst Fleury, São Paulo, Brazil
dc.description.affiliationUnifespUniversidade Federal de São Paulo, Dept Microbiol Immunol & Parasitol, São Paulo, Brazil
dc.description.sourceWeb of Science

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