Dermabrasion for Acne Scars During Treatment with Oral Isotretinoin

Dermabrasion for Acne Scars During Treatment with Oral Isotretinoin

Author Bagatin, Edileia Autor UNIFESP Google Scholar
Santos Guadanhim, Lilia Ramos dos Autor UNIFESP Google Scholar
Yarak, Samira Autor UNIFESP Google Scholar
Leao Kamamoto, Cristhine Souza Autor UNIFESP Google Scholar
Almeida, Fernando Augusto de Autor UNIFESP Google Scholar
Institution Universidade Federal de São Paulo (UNIFESP)
Abstract BACKGROUND Oral isotretinoin is the criterion standard treatment for severe inflammatory acne associated with scar development. Atypical or exaggerated cicatrization related to oral isotretinoin was reported throughout the 1980s and 1990s. Dermabrasion for atrophic acne scar revision is not recommended 6 to 12 months from the end of oral isotretinoin treatment.OBJECTIVE To evaluate wound healing after localized dermabrasion in patients receiving oral isotretinoin.MATERIALS & METHODS Interventional, prospective study involving seven patients taking oral isotretinoin to treat acne and with atrophic acne scars on the face. Manual dermabrasion was performed on all patients in an area of approximately 1 cm 2, and a 6-month reepithelization follow-up by clinical evaluation was conducted.RESULTS All patients presented normal cicatrization evolution; hypertrophic scarring or keloid as a result of localized abrasion was not observed, and atrophic acne scar revision result was excellent.CONCLUSION the current recommendation to wait 6 to 12 months after treatment with oral isotretinoin for acne scar revision using dermabrasion should be re-evaluated. Abrasion of a small test area may be a useful predictor of wound healing, enabling earlier acne scar treatment using this procedure.
Language English
Sponsor Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)
Date 2010-04-01
Published in Dermatologic Surgery. Malden: Wiley-Blackwell Publishing, Inc, v. 36, n. 4, p. 483-489, 2010.
ISSN 1076-0512 (Sherpa/Romeo, impact factor)
Publisher Wiley-Blackwell
Extent 483-489
Access rights Closed access
Type Article
Web of Science ID WOS:000276168500007

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