The use of disulfiram for alcohol-dependent patients and duration of outpatient treatment

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Elbreder, Marcia Fonsi [UNIFESP]
Humerez, Dorisdaia Carvalho de
Laranjeira, Ronaldo [UNIFESP]
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Despite the fact that alcoholism is a severe public health problem of worldwide proportions, only a limited number of medications is used as coadjuvant treatment. the objectives of this study were to analyse the use of disulfiram for alcohol-dependent patients and the immediate interruption of treatment following medication prescription. This is a transversal study of 810 patients who attended the Alcohol and Drug Research Unit (UNIAD) during the 20002006 period. the study showed that both male and female patients who had remained under treatment during the first year used proportionally more disulfiram than those who remained for lesser time under treatment, and immediate treatment interruption was statistically more significant in this latter group of patients after prescription of this medication. Although disulfiram is an old medication, it seems that this drug can be useful for keeping alcohol-dependent patients under outpatient treatment.
European Archives of Psychiatry and Clinical Neuroscience. Heidelberg: Dr Dietrich Steinkopff Verlag, v. 260, n. 3, p. 191-195, 2010.