Factors associated with nutritional status in liver transplant patients who survived the first year after transplantation

Factors associated with nutritional status in liver transplant patients who survived the first year after transplantation

Author Carvalho, Luciana de Autor UNIFESP Google Scholar
Parise, Edison Roberto Autor UNIFESP Google Scholar
Samuel, Didier Google Scholar
Institution Universidade Federal de São Paulo (UNIFESP)
Univ Paris 11
Abstract Background and Aims: Most studies published focus on the evaluation of the impact of nutritional status on the morbidity and mortality during the immediate postoperative period or on the short-term evolution of liver transplant patients. the aim of the study was to evaluate long-term trends in nutritional status.Methods: Seventy patients consecutively submitted to liver transplantation were studied. Nutritional assessment was performed the day before transplantation and the 45, 90, 180 and 365 days after transplantation, consisting of determination of dietary intake, anthropometric and biochemical analysis.Results: Sixty-nine percent of the patients presented with malnutrition on the day before liver transplantation, decreasing to 44% at end of the first year. the prevalence of protein-calorie malnutrition (PCM) was 63% at 90 days post-transplant. A significant difference of PCM was observed between patients with cirrhosis and non-cirrhotic disease (53.6% x 100%) at 90 days post-transplant. the pre-transplant nutritional diagnosis and 90-day calorie intake were identified as variables independently associated with nutritional status at 90 days post-transplant. the variables independently associated with nutritional status in the 1-year assessment were pre-transplant PCM and 365-day calorie requirements.Conclusion: No influence on nutritional status was observed for peri- or postoperative factors after 3 or 12 months of follow up. As expected, dietary factors, especially adequate calorie intake, were always associated with nutritional status during all periods analyzed.
Keywords anthropometry
cirrhosis
liver transplantation
nutritional status
Language English
Sponsor Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)
Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)
Date 2010-02-01
Published in Journal of Gastroenterology and Hepatology. Malden: Wiley-Blackwell Publishing, Inc, v. 25, n. 2, p. 391-396, 2010.
ISSN 0815-9319 (Sherpa/Romeo, impact factor)
Publisher Wiley-Blackwell
Extent 391-396
Origin http://dx.doi.org/10.1111/j.1440-1746.2009.06033.x
Access rights Closed access
Type Article
Web of Science ID WOS:000274184500030
URI http://repositorio.unifesp.br/handle/11600/32252

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