Stereoselective Nucleophilic Addition of Potassium Alkyltrifluoroborates to Cyclic N-Acyliminium Ions: a Simple and Mild Approach to Chiral 5-Alkyl-pyrrolidin-2-ones
Vieira, Adriano S.
Ferreira, Fernando P. [UNIFESP]
Guarezemini, Alexandre S.
Stefani, Helio A. [UNIFESP]
Is part ofAustralian Journal of Chemistry
MetadataShow full item record
The stereoselective nucleophilic addition of potassium alkyltrifluoroborates to cyclic N-acyliminium ions derived from N-benzyl-3,4,5-triacetoxy-pyrrolidin-2-one, which affords 5-substituted-pyrrolidin-2-ones, is described. the products are obtained in moderate to good yields and are produced predominantly as the anti diastereomer.
CitationAustralian Journal of Chemistry. Collingwood: Csiro Publishing, v. 62, n. 8, p. 909-916, 2009.
- EPM - Artigos